piperacillin--tazobactam-drug-combination and Corneal-Ulcer

To report the treatment of therapy-resistant Pseudomonas aeruginosa keratitis with topical piperacillin/tazobactam.. Retrospective report of 3 cases.. Three patients with P. aeruginosa keratitis were unresponsive to various antimicrobials. Resolution of all 3 cases of keratitis occurred upon commencement of topical piperacillin/tazobactam.. Therapy-resistant P. aeruginosa keratitis acquired from the community is becoming an increasing problem. Topical piperacillin/tazobactam is an option for the treatment of therapy-resistant P. aeruginosa keratitis.

Topics: Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Corneal Ulcer; Drug Resistance; Eye Infections, Bacterial; Humans; Male; Middle Aged; Ophthalmic Solutions; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prognosis; Pseudomonas Infections; Retrospective Studies