pipemidic acid has been researched along with Urinary Tract Infections in 46 studies
Pipemidic Acid: Antimicrobial against Gram negative and some Gram positive bacteria. It is protein bound and concentrated in bile and urine and used for gastrointestinal, biliary, and urinary infections.
pipemidic acid : A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid substituted at position 2 by a piperazin-1-yl group and at position 8 by an ethyl group. A synthetic broad-spectrum antibacterial, it is used for treatment of gastrointestinal, biliary, and urinary infections.
Urinary Tract Infections: Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Norfloxacin (NOR) was compared to pipemidic acid (PA) in complicated urinary tract infections (UTIs) caused by pathogens susceptible to both agents to evaluate the antibacterial activity of the new 4-quinolone derivative." | 9.06 | Norfloxacin versus pipemidic acid in complicated urinary tract infections due to susceptible pathogens: a comparative clinical trial. ( Boldrini, F; Del Favero, A; Frongillo, RF; Guerciolini, R; Menichetti, F; Pauluzzi, S, 1986) |
| "In an open uncontrolled trial 60 women with confirmed uncomplicated urinary tract infections were randomly allocated to receive either pipemidic acid (Septidron; Ethimed) or nitrofurantoin for 10 days." | 9.06 | A comparative study of pipemidic acid and nitrofurantoin in the treatment of uncomplicated urinary tract infections. ( Meyer, EC; Schoeman, HS, 1987) |
| "The clinical efficacy, safety and usefulness of DL-8280 for the treatment of complicated urinary tract infections were compared with those of pipemidic acid (PPA) by a double-blind method." | 9.05 | [Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method]. ( Deguchi, K; Fujita, Y; Kishi, H; Niijima, T; Nishimura, Y; Nito, H; Ogawa, N; Ohmori, H; Saito, I; Tanaka, H, 1984) |
| "Fosfomycin trometamol (FOT), a new soluble salt of fosfomycin, was developed especially for single-dose treatment in uncomplicated urinary tract infections." | 7.67 | Microbiological basis for the use of fosfomycin trometamol as single-dose therapy for simple cystitis. ( Chisari, G; Gismondo, MR; Lo Bue, AM; Nicoletti, G; Romeo, MA, 1986) |
| "The clinical efficacy, safety and usefulness of DL-8280 for the treatment of complicated urinary tract infections were compared with those of pipemidic acid (PPA) by a double-blind method." | 5.05 | [Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method]. ( Deguchi, K; Fujita, Y; Kishi, H; Niijima, T; Nishimura, Y; Nito, H; Ogawa, N; Ohmori, H; Saito, I; Tanaka, H, 1984) |
| "Fosfomycin trometamol (FOT), a new soluble salt of fosfomycin, was developed especially for single-dose treatment in uncomplicated urinary tract infections." | 3.67 | Microbiological basis for the use of fosfomycin trometamol as single-dose therapy for simple cystitis. ( Chisari, G; Gismondo, MR; Lo Bue, AM; Nicoletti, G; Romeo, MA, 1986) |
| " Among quinolones, the most active agents are ciprofloxacin and ofloxacin (MIC modes: 4 and 2 mg/l), so these antimicrobials could be used for the treatment of urinary tract infections caused by Corynebacterium group D2." | 3.67 | [Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity]. ( Cancet, B; Clave, D; Didier, J; Henry-Ferry, S; Marty, N, 1988) |
| "The in vitro activity of the quinolone derivative flumequine against 1918 bacterial strains, isolated from urinary tract infections, has been compared to the antibacterial activity of other compounds, such as pipemidic acid, oxolinic acid and cefazolin." | 3.67 | [Evaluation of the in vitro activity of flumequine on bacterial strains recently isolated in the hospital]. ( Amato, G; Anzivino, D; Covelli, I; Nani, E, 1986) |
| "Urinary Tract Infections are the largest group of infections after the respiratory tract infections." | 2.80 | Clinical evaluation of herbal coded formulation Cran-off to Urixin in the treatment of urinary tract infection. ( Akhtar, N; Nazar, H; Shaheen, G; Usmanghani, K, 2015) |
| "Pipemidic acid was studied according to that model--the acid being a new chemotherapeutic, similar to nalidixic acid according to chemical composition and action." | 2.66 | [Clinical trial of drugs for treating urological infections--pipemidic acid]. ( Angelova, I; Belovezhdov, N; Chakŭrski, I; Koĭchev, A; Talakova, Ch, 1985) |
| " Fecal samples were collected before, during, and after therapy from 23 adults who were undergoing treatment of urinary tract infections with pipemidic acid at a dosage of 200 mg orally four times daily for 10 days." | 1.27 | Selective decontamination of the digestive tract by pipemidic acid. ( Boerema, HB; Muytjens, HL; van der Ros-van de Repe, J; van der Waaij, D; van Veldhuizen, GL; Welling, GW, 1983) |
| "The pharmacokinetic profile of pipemidic acid was studied in two groups of young healthy volunteers by using a new, sensitive, high-pressure liquid chromatography procedure for quantitation of pipemidic acid in biological fluids." | 1.27 | Single- and multiple-dose pharmacokinetics of pipemidic acid in normal human volunteers. ( Hänninen, U; Klinge, E; Männistö, PT; Mäntylä, R; Mattila, J, 1984) |
| "Incidence of recurrence of UTI in 48 patients with uncomplicated UTI and 10 patients with complicated UTI decreased to 0." | 1.27 | [Clinical studies of antimicrobial prophylaxis of recurrent urinary infection in women. Long-term, low-dose pipemidic acid for prophylaxis]. ( Fujii, M; Hatachi, K; Hayashi, M; Hirayama, M; Masu, C; Matsuki, S; Nakano, H; Nihira, H; Shiraishi, T; Sumii, T, 1984) |
| "Ciprofloxacin was the most active agent." | 1.27 | In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species. ( Allocati, N; Cellini, L; Di Girolamo, A; Piccolomini, R; Scazzocchio, F; Selan, L, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (82.61) | 18.7374 |
| 1990's | 5 (10.87) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (4.35) | 24.3611 |
| 2020's | 1 (2.17) | 2.80 |
| Authors | Studies |
|---|---|
| Mumtaz, K | 1 |
| Munir, S | 1 |
| Muddassir, M | 1 |
| Raza, A | 1 |
| Waqas, K | 1 |
| Shoaib Ahmed, S | 1 |
| Malik, A | 1 |
| Haider Naqvi, SZ | 1 |
| Chiang, BJ | 1 |
| Pu, YS | 1 |
| Chung, SD | 1 |
| Liu, SP | 1 |
| Yu, HJ | 1 |
| Wang, SM | 1 |
| Chang, HC | 1 |
| Chiang, IN | 1 |
| Huang, CY | 1 |
| Shaheen, G | 1 |
| Usmanghani, K | 1 |
| Nazar, H | 1 |
| Akhtar, N | 1 |
| Kishi, H | 1 |
| Nito, H | 1 |
| Saito, I | 1 |
| Nishimura, Y | 1 |
| Niijima, T | 1 |
| Ohmori, H | 1 |
| Tanaka, H | 1 |
| Fujita, Y | 1 |
| Deguchi, K | 1 |
| Ogawa, N | 1 |
| Schüller, J | 1 |
| Walther, V | 1 |
| Mayer, P | 1 |
| Marx, FJ | 1 |
| Muytjens, HL | 1 |
| van Veldhuizen, GL | 1 |
| Welling, GW | 1 |
| van der Ros-van de Repe, J | 1 |
| Boerema, HB | 1 |
| van der Waaij, D | 1 |
| Kamran, MA | 1 |
| Ali, S | 1 |
| Khattak, KN | 1 |
| Hirai, K | 1 |
| Ito, A | 1 |
| Abe, Y | 1 |
| Suzue, S | 1 |
| Irikura, T | 1 |
| Inoue, M | 1 |
| Mitsuhashi, S | 1 |
| Klinge, E | 1 |
| Männistö, PT | 1 |
| Mäntylä, R | 1 |
| Mattila, J | 1 |
| Hänninen, U | 1 |
| Masu, C | 1 |
| Sumii, T | 1 |
| Hatachi, K | 1 |
| Hayashi, M | 1 |
| Nakano, H | 1 |
| Nihira, H | 1 |
| Hirayama, M | 1 |
| Shiraishi, T | 1 |
| Matsuki, S | 1 |
| Fujii, M | 1 |
| Pagani, G | 2 |
| Oosterlinck, W | 1 |
| Welvaert, P | 1 |
| Verbaeys, A | 1 |
| Schelfout, W | 1 |
| Wijndaele, JJ | 1 |
| de Maeyer, P | 1 |
| Hussain, Z | 1 |
| Burchardt, P | 1 |
| Bischoff, W | 1 |
| Azanza Perea, JR | 1 |
| Honorato Pérez, JM | 1 |
| Cuena Boy, R | 1 |
| Cantore, R | 1 |
| Pedone, V | 1 |
| Grimm, H | 1 |
| Martini, G | 1 |
| Romano, G | 2 |
| Donà, G | 1 |
| Negri, M | 1 |
| Di Silverio, F | 1 |
| Criniti, P | 1 |
| Zezza, A | 1 |
| Galfano, G | 1 |
| Fernández Fernández, A | 1 |
| Lantero Benedito, M | 1 |
| Gastañares Hernando, MJ | 1 |
| Undabeitia Santisteban, E | 1 |
| Fernández Santos, F | 1 |
| Castaño Rodríguez, A | 1 |
| Gil Fabra, J | 1 |
| Martínez Castellanos, F | 1 |
| Otero Mauricio, G | 1 |
| Pérez-Trallero, E | 1 |
| Urbieta, M | 1 |
| Jimenez, D | 1 |
| García-Arenzana, JM | 1 |
| Cilla, G | 1 |
| Ueda, Y | 1 |
| Matsumoto, F | 1 |
| Saito, A | 1 |
| Ohkoshi, M | 1 |
| Kawamura, N | 1 |
| Nishiura, T | 2 |
| Kawada, Y | 2 |
| Ban, Y | 1 |
| Hofstetter, A | 1 |
| Langsádl, L | 1 |
| Polívková-Konícková, L | 1 |
| Roubínek, F | 1 |
| Schilirò, S | 1 |
| D'Asta, S | 1 |
| Jelińska, S | 1 |
| Gietko, G | 1 |
| Ponce de León Roca, M | 1 |
| Caballero Domènech, JC | 1 |
| Aguilar Sánchez, M | 1 |
| León Sanromá, M | 1 |
| Fernández Ferré, ML | 1 |
| Cortés, R | 1 |
| Pascual, T | 1 |
| Lou Arnal, S | 1 |
| Orozco, F | 1 |
| Sunyer, L | 1 |
| Malinova, M | 1 |
| Grozdanov, G | 1 |
| Masarliev, A | 1 |
| Obana, Y | 1 |
| Nishino, T | 1 |
| Gismondo, MR | 1 |
| Romeo, MA | 1 |
| Lo Bue, AM | 1 |
| Chisari, G | 1 |
| Nicoletti, G | 1 |
| Marty, N | 1 |
| Clave, D | 1 |
| Cancet, B | 1 |
| Henry-Ferry, S | 1 |
| Didier, J | 1 |
| Esposito, S | 1 |
| Galante, D | 1 |
| Pennucci, C | 1 |
| Barba, D | 1 |
| Piccolomini, R | 1 |
| Cellini, L | 1 |
| Allocati, N | 1 |
| Di Girolamo, A | 1 |
| Selan, L | 1 |
| Scazzocchio, F | 1 |
| Wittenberger, R | 1 |
| van Oosterom, RA | 1 |
| Hartman, EG | 1 |
| Del Favero, A | 1 |
| Frongillo, RF | 1 |
| Menichetti, F | 1 |
| Boldrini, F | 1 |
| Guerciolini, R | 1 |
| Pauluzzi, S | 1 |
| Careddu, P | 1 |
| Borzani, M | 1 |
| Scotti, L | 1 |
| Varotto, F | 1 |
| Garlaschi, L | 1 |
| Fontana, P | 1 |
| Meyer, EC | 1 |
| Schoeman, HS | 1 |
| Nani, E | 1 |
| Amato, G | 1 |
| Anzivino, D | 1 |
| Covelli, I | 1 |
| Mascellino, MT | 1 |
| Lorenzi, A | 1 |
| Bonanni, M | 1 |
| Iegri, F | 1 |
| Belovezhdov, N | 1 |
| Talakova, Ch | 1 |
| Angelova, I | 1 |
| Chakŭrski, I | 1 |
| Koĭchev, A | 1 |
| Minkov, N | 1 |
| Zlatanov, Z | 1 |
| Zozikov, B | 1 |
| Khristova, D | 1 |
13 trials available for pipemidic acid and Urinary Tract Infections
| Article | Year |
|---|---|
Quinolone prophylaxis in transrectal ultrasound guided prostate biopsy: an eight-year single center experience.
Topics: Antibiotic Prophylaxis; Biopsy; Cefazolin; Humans; Levofloxacin; Male; Pipemidic Acid; Prostate; Ret | 2013 |
Clinical evaluation of herbal coded formulation Cran-off to Urixin in the treatment of urinary tract infection.
Topics: Adolescent; Adult; Anti-Infective Agents, Urinary; Female; Humans; Male; Middle Aged; Phytotherapy; | 2015 |
[Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method].
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Clinical Trials as T | 1984 |
[Clinical contribution to the study of pipemidic acid in urinary tract infections in a urology clinic].
Topics: Adult; Aged; Bacteriuria; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nicotinic Aci | 1980 |
[Pipemidic acid: a new antibiotic for the urinary tract. A comparative, double-blind study of pipemidic acid and amoxidillin].
Topics: Amoxicillin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nicot | 1980 |
[Pipemidic acid in the treatment of various infective disorders of the urinary tract in a series of obstetric and gynecologic patients].
Topics: Adult; Bacterial Infections; Female; Genital Diseases, Female; Humans; Nalidixic Acid; Nicotinic Aci | 1979 |
[Single oral dose of phosphomycin trometamol versus pipemidic acid and norfloxacin in treating uncomplicated low-level urinary tract infections].
Topics: Administration, Oral; Adult; Aged; Drug Administration Schedule; Female; Fosfomycin; Humans; Middle | 1992 |
[The clinical trial and use of the preparation Palin in urogenital infections].
Topics: Administration, Intravaginal; Adolescent; Adult; Bacterial Infections; Capsules; Female; Genital Dis | 1990 |
[Ofloxacin versus pipemidic acid and co-trimoxazole].
Topics: Adult; Anti-Infective Agents, Urinary; Bacteria; Bacterial Infections; Clinical Trials as Topic; Dos | 1986 |
Norfloxacin versus pipemidic acid in complicated urinary tract infections due to susceptible pathogens: a comparative clinical trial.
Topics: Clinical Trials as Topic; Drug Resistance, Microbial; Escherichia coli; Female; Humans; Klebsiella; | 1986 |
Treatment of lower urinary tract infections in children: single dose fosfomycin trometamol versus pipemidic acid.
Topics: Adolescent; Child; Child, Preschool; Enterobacteriaceae; Feces; Female; Fosfomycin; Humans; Infant; | 1987 |
A comparative study of pipemidic acid and nitrofurantoin in the treatment of uncomplicated urinary tract infections.
Topics: Adult; Female; Humans; Nicotinic Acids; Nitrofurantoin; Pipemidic Acid; Time Factors; Urinary Tract | 1987 |
[Clinical trial of drugs for treating urological infections--pipemidic acid].
Topics: Adult; Aged; Bacteria; Bacterial Infections; Clinical Trials as Topic; Female; Humans; Male; Microbi | 1985 |
33 other studies available for pipemidic acid and Urinary Tract Infections
| Article | Year |
|---|---|
Antibiogram and molecular characterization of multi-drug resistant microorganisms isolated from urinary tract infections.
Topics: Amikacin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ciprofloxacin; Drug | 2021 |
[Treatment of urinary tract infections with pipemidic acid and cotrimoxazol. A comparative study].
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Drug Combinations; Female; Humans; Male; Middle Aged; N | 1983 |
Selective decontamination of the digestive tract by pipemidic acid.
Topics: Adolescent; Adult; Aged; Digestive System; Dipeptides; Enterobacteriaceae; Feces; Female; Humans; Ma | 1983 |
Therapeutic evaluation of pipemidic acid (R-Urexin) in urinary tract infection. A preliminary report.
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Nicotinic Acids; Pipemidic Acid; Urinary Tract | 1984 |
Comparative activities of AM-715 and pipemidic and nalidixic acids against experimentally induced systemic and urinary tract infections.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Mice; Nalidixic Acid; Nicotinic Acids; Norflox | 1981 |
Single- and multiple-dose pharmacokinetics of pipemidic acid in normal human volunteers.
Topics: Adult; Biological Availability; Blood Proteins; Female; Humans; Kinetics; Male; Nicotinic Acids; Pip | 1984 |
[Clinical studies of antimicrobial prophylaxis of recurrent urinary infection in women. Long-term, low-dose pipemidic acid for prophylaxis].
Topics: Drug Evaluation; Female; Humans; Nicotinic Acids; Pipemidic Acid; Premedication; Recurrence; Urinary | 1984 |
[Therapy of noncomplicated urinary tract infections in women].
Topics: Ampicillin; Escherichia coli Infections; Female; Humans; Nalidixic Acid; Nitrofurantoin; Pipemidic A | 1981 |
[Pipemidic acid--an alternative in the oral treatment of urinary tract infections and prostatitis].
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Nicotinic A | 1982 |
[Pipemidic acid].
Topics: Bacteria; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Kidne | 1982 |
[Pipemidic acid in urinary infections of geriatric patients].
Topics: Aged; Female; Humans; Male; Middle Aged; Nicotinic Acids; Pipemidic Acid; Urinary Tract Infections | 1980 |
[Comparative bacteriologic in vitro studies with pipemidic acid and nalidixic acid].
Topics: Humans; In Vitro Techniques; Microbial Sensitivity Tests; Nalidixic Acid; Nicotinic Acids; Pipemidic | 1980 |
[Clinical results of the use of pipemidic acid in the common urinary tract infections].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Female; Humans; Male; Middle Aged; Nicotinic Acids; P | 1980 |
[Pipemidic acid in urinary tract infections in aged patients].
Topics: Age Factors; Aged; Bacterial Infections; Female; Humans; Male; Middle Aged; Nicotinic Acids; Pipemid | 1980 |
[Significance and importance of the use of pipemidic acid in the therapy of acute and chronic urinary tract infections].
Topics: Acute Disease; Adult; Bacteria; Bacterial Infections; Chronic Disease; Female; Humans; Male; Microbi | 1980 |
[Quinolone-resistant Escherichia coli in the health area of a 650-bed hospital].
Topics: Catchment Area, Health; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Hospital Bed Ca | 1994 |
Ten-year survey of quinolone resistance in Escherichia coli causing urinary tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Data Collection; Drug Resistance, Microbial; Escherichia coli; | 1993 |
Clinical studies on pipemidic acid.
Topics: Administration, Oral; Adolescent; Adult; Aged; Animals; Child; Drug Resistance, Microbial; Escherich | 1978 |
[Method for clinical evaluation of antimicrobial agents on urinary tract infections. II. Criteria for complicated urinary tract infections (author's transl)].
Topics: Adolescent; Adult; Ampicillin; Anti-Bacterial Agents; Bacteriuria; Carbenicillin; Drug Evaluation; F | 1979 |
[Deblaston].
Topics: Drug Evaluation; Humans; Nicotinic Acids; Pipemidic Acid; Urinary Tract Infections | 1979 |
[A comparison of the effects of three urinary infection chemotherapeutics - nalidixic, oxolinic, and pipemidic acids (author's transl)].
Topics: Animals; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Microbial Sensitiv | 1979 |
[Use of pipemidic acid in the treatment of urinary tract infections].
Topics: Adult; Aged; Bacterial Infections; Cystitis; Female; Humans; Male; Middle Aged; Nalidixic Acid; Nico | 1979 |
[Use of pipram in the treatment of urinary tract infections].
Topics: Administration, Oral; Adult; Aged; Drug Tolerance; Female; Humans; Male; Middle Aged; Nicotinic Acid | 1978 |
[The treatment of uncomplicated lower-urinary tract infection: a single dose of trimethoprim as opposed to 10 days with pipemidic acid].
Topics: Adolescent; Adult; Aged; Drug Evaluation; Female; Humans; Middle Aged; Pipemidic Acid; Time Factors; | 1992 |
In vivo activity of ciprofloxacin, ofloxacin, norfloxacin and pipemidic acid against Escherichia coli infections in mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Mice; Microbial | 1989 |
Microbiological basis for the use of fosfomycin trometamol as single-dose therapy for simple cystitis.
Topics: Bacteria; Cystitis; Drug Combinations; Escherichia coli; Fosfomycin; Humans; Microbial Sensitivity T | 1986 |
[Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium; Corynebacterium Infections; Drug Resistance, | 1988 |
Occurrence of gram negative bacteria in midstream bladder urine and their sensitivity to quinoline derivatives.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Drug Resistance, Microbial; Female; Gram-Ne | 1985 |
In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalid | 1988 |
Pipemidic acid, a new treatment for recurrent urinary tract infection in small animals.
Topics: Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Escherichia coli Infections; Nicotinic Acids; Pipem | 1986 |
[Evaluation of the in vitro activity of flumequine on bacterial strains recently isolated in the hospital].
Topics: Bacteria; Cefazolin; Fluoroquinolones; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Oxo | 1986 |
Antimicrobial activity of norfloxacin in enteric and urinary tract infections: combined effect of norfloxacin with aminoglycosides, tetracycline and chloramphenicol.
Topics: Acinetobacter; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Chloramphenicol; Drug C | 1986 |
[Pipemidinic acid as a urinary antiseptic--microbiological and clinical study].
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteria; Humans; Nicotinic | 1985 |