pipemidic acid has been researched along with Kidney Failure, Chronic in 4 studies
Pipemidic Acid: Antimicrobial against Gram negative and some Gram positive bacteria. It is protein bound and concentrated in bile and urine and used for gastrointestinal, biliary, and urinary infections.
pipemidic acid : A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid substituted at position 2 by a piperazin-1-yl group and at position 8 by an ethyl group. A synthetic broad-spectrum antibacterial, it is used for treatment of gastrointestinal, biliary, and urinary infections.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The main pharmacokinetic parameters were: tmax, 2." | 1.27 | Pharmacokinetics of pipemidic acid in healthy middle-aged volunteers and elderly patients with renal insufficiency. ( Gordin, A; Hänninen, U; Männistö, P; Mäntylä, R; Niinistö, L; Salo, H; Solkinen, A, 1984) |
| "5 to 36 ml/mn the dosage was 11." | 1.26 | [Utilisation of pipemidic acid as antibiotic in patients with renal failure insufficiency. Kinetics of serum and urinary concentrations (author's transl)]. ( Kourilsky, O; Le Verge, R; Meyrier, A; Montay, G, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Männistö, P | 1 |
| Solkinen, A | 1 |
| Mäntylä, R | 1 |
| Gordin, A | 1 |
| Salo, H | 1 |
| Hänninen, U | 1 |
| Niinistö, L | 1 |
| Azanza Perea, JR | 1 |
| Honorato Pérez, JM | 1 |
| Cuena Boy, R | 1 |
| Meyrier, A | 2 |
| Verger, C | 1 |
| Kourilsky, O | 2 |
| Montay, G | 1 |
| Le Verge, R | 1 |
1 trial available for pipemidic acid and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Use of pipemidic acid as an extra-urinary antibiotic in renal insufficiency and hemodialysis (proceedings)].
Topics: Clinical Trials as Topic; Drug Tolerance; Endocarditis, Bacterial; Enterobacteriaceae Infections; Es | 1978 |
3 other studies available for pipemidic acid and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pharmacokinetics of pipemidic acid in healthy middle-aged volunteers and elderly patients with renal insufficiency.
Topics: Adult; Aged; Aging; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Microbial Sensitivity T | 1984 |
[Pipemidic acid].
Topics: Bacteria; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Kidne | 1982 |
[Utilisation of pipemidic acid as antibiotic in patients with renal failure insufficiency. Kinetics of serum and urinary concentrations (author's transl)].
Topics: Administration, Oral; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Humans; Kidney Failur | 1979 |