pipemidic acid has been researched along with Bacterial Disease in 22 studies
Pipemidic Acid: Antimicrobial against Gram negative and some Gram positive bacteria. It is protein bound and concentrated in bile and urine and used for gastrointestinal, biliary, and urinary infections.
pipemidic acid : A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid substituted at position 2 by a piperazin-1-yl group and at position 8 by an ethyl group. A synthetic broad-spectrum antibacterial, it is used for treatment of gastrointestinal, biliary, and urinary infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clinical efficacy, safety and usefulness of lomefloxacin (LFLX, NY-198), a new quinolone antimicrobial agent, were compared with those of pipemidic acid (PPA) in the treatment of infectious enteritis (bacillary dysentery, enteropathogenic Escherichia coli enteritis and Campylobacter enteritis) by a double blind method." | 9.06 | [Comparison of clinical efficacy of lomefloxacin (LFLX, NY-198) and pipemidic acid (PPA) in the treatment of infectious enteritis by a double-blind method. The Japan Research Committee of Lomefloxacin Research Group Enteritis]. ( Aoki, T; Kanehisa, N; Matsubara, Y; Murata, M; Nitta, Y; Sagara, H; Seo, T; Shimizu, N; Takizawa, Y; Tomizawa, I, 1989) |
| "The therapeutic effectiveness of a single oral dose (60 and 200 mg/kg body weight) of fosfomycin trometamol (FT), norfloxacin, trimethoprim sulfamethoxazole (Bactrim) and pipemidic acid against experimental cystitis in the rat were compared." | 7.67 | Treatment of experimental cystitis in the rat with a single dose of fosfomycin trometamol. ( Dubini, F; Riviera, L, 1988) |
| "The clinical efficacy, safety and usefulness of lomefloxacin (LFLX, NY-198), a new quinolone antimicrobial agent, were compared with those of pipemidic acid (PPA) in the treatment of infectious enteritis (bacillary dysentery, enteropathogenic Escherichia coli enteritis and Campylobacter enteritis) by a double blind method." | 5.06 | [Comparison of clinical efficacy of lomefloxacin (LFLX, NY-198) and pipemidic acid (PPA) in the treatment of infectious enteritis by a double-blind method. The Japan Research Committee of Lomefloxacin Research Group Enteritis]. ( Aoki, T; Kanehisa, N; Matsubara, Y; Murata, M; Nitta, Y; Sagara, H; Seo, T; Shimizu, N; Takizawa, Y; Tomizawa, I, 1989) |
| "The therapeutic effectiveness of a single oral dose (60 and 200 mg/kg body weight) of fosfomycin trometamol (FT), norfloxacin, trimethoprim sulfamethoxazole (Bactrim) and pipemidic acid against experimental cystitis in the rat were compared." | 3.67 | Treatment of experimental cystitis in the rat with a single dose of fosfomycin trometamol. ( Dubini, F; Riviera, L, 1988) |
| "Pipemidic acid was studied according to that model--the acid being a new chemotherapeutic, similar to nalidixic acid according to chemical composition and action." | 2.66 | [Clinical trial of drugs for treating urological infections--pipemidic acid]. ( Angelova, I; Belovezhdov, N; Chakŭrski, I; Koĭchev, A; Talakova, Ch, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (86.36) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsumoto, J | 1 |
| Miyamoto, T | 1 |
| Minamida, A | 1 |
| Nishimura, Y | 1 |
| Egawa, H | 1 |
| Nishimura, H | 1 |
| Nakamura, S | 1 |
| Nakata, K | 1 |
| Katae, H | 1 |
| Minami, A | 1 |
| Kashimoto, S | 1 |
| Yamagishi, J | 1 |
| Takase, Y | 1 |
| Shimizu, M | 1 |
| Kouno, K | 1 |
| Inoue, M | 3 |
| Mitsuhashi, S | 3 |
| Hashimoto, H | 1 |
| Sagara, H | 2 |
| Matsubara, Y | 3 |
| Tomizawa, I | 3 |
| Takizawa, Y | 3 |
| Ito, K | 2 |
| Konishi, K | 2 |
| Matsunaga, M | 2 |
| Yanagishita, T | 2 |
| Kosugi, M | 2 |
| Saito, M | 1 |
| Seo, T | 2 |
| Hirai, K | 1 |
| Ito, A | 1 |
| Abe, Y | 1 |
| Suzue, S | 1 |
| Irikura, T | 1 |
| Martini, G | 1 |
| Romano, G | 2 |
| Donà, G | 1 |
| Negri, M | 1 |
| Di Silverio, F | 1 |
| Criniti, P | 1 |
| Zezza, A | 1 |
| Galfano, G | 1 |
| Archimbaud, JP | 1 |
| Leriche, A | 1 |
| Schilirò, S | 1 |
| D'Asta, S | 1 |
| Pagani, G | 1 |
| Khristov, A | 1 |
| Zlatkov, V | 1 |
| Dimitrov, A | 1 |
| Malinova, M | 1 |
| Grozdanov, G | 1 |
| Masarliev, A | 1 |
| Papazova, I | 1 |
| Stoianova, V | 1 |
| Kozovski, I | 1 |
| Sampi, K | 1 |
| Sakurai, M | 1 |
| Kumai, R | 1 |
| Maseki, N | 1 |
| Kaneko, Y | 1 |
| Hattori, M | 1 |
| Aoki, T | 1 |
| Shimizu, N | 1 |
| Nitta, Y | 1 |
| Kanehisa, N | 1 |
| Murata, M | 1 |
| Dubini, F | 1 |
| Riviera, L | 1 |
| Hirose, T | 1 |
| Okezaki, E | 1 |
| Kato, H | 1 |
| Ito, Y | 1 |
| Wittenberger, R | 1 |
| Mascellino, MT | 1 |
| Lorenzi, A | 1 |
| Bonanni, M | 1 |
| Iegri, F | 1 |
| Belovezhdov, N | 1 |
| Talakova, Ch | 1 |
| Angelova, I | 1 |
| Chakŭrski, I | 1 |
| Koĭchev, A | 1 |
9 trials available for pipemidic acid and Bacterial Disease
| Article | Year |
|---|---|
[Comparison of clinical usefulness of enoxacin (ENX, AT-2266) and pipemidic acid (PPA) in the treatment of acute infectious diarrhea by a double-blind method. The Japan Research Committee of Enoxacin Research Group for Acute Infectious Diarrhea].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Clinical Trials as T | 1984 |
[Comparison of clinical efficacy of ofloxacin COFLX: DL-8280) and pipemidic acid (PPA) in acute infectious diarrhea by a double-blind method. The Japan Research Committee of Ofloxacin, Research Group for Acute Infectious Diarrhea].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Campylobacter I | 1984 |
[Pipemidic acid in the treatment of various infective disorders of the urinary tract in a series of obstetric and gynecologic patients].
Topics: Adult; Bacterial Infections; Female; Genital Diseases, Female; Humans; Nalidixic Acid; Nicotinic Aci | 1979 |
[A clinical trial of the preparation palin in women with refractory colpitis].
Topics: Bacteria; Bacterial Infections; Chronic Disease; Drug Therapy, Combination; Female; Humans; Microbia | 1990 |
[The clinical trial and use of the preparation Palin in urogenital infections].
Topics: Administration, Intravaginal; Adolescent; Adult; Bacterial Infections; Capsules; Female; Genital Dis | 1990 |
Combination of pipemidic acid, colistin sodium methanesulfonate and nystatin may be less effective than nystatin alone for prevention of infection during chemotherapy-induced granulocytopenia in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; B | 1989 |
[Comparison of clinical efficacy of lomefloxacin (LFLX, NY-198) and pipemidic acid (PPA) in the treatment of infectious enteritis by a double-blind method. The Japan Research Committee of Lomefloxacin Research Group Enteritis].
Topics: 4-Quinolones; Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Double-Blind Met | 1989 |
[Ofloxacin versus pipemidic acid and co-trimoxazole].
Topics: Adult; Anti-Infective Agents, Urinary; Bacteria; Bacterial Infections; Clinical Trials as Topic; Dos | 1986 |
[Clinical trial of drugs for treating urological infections--pipemidic acid].
Topics: Adult; Aged; Bacteria; Bacterial Infections; Clinical Trials as Topic; Female; Humans; Male; Microbi | 1985 |
13 other studies available for pipemidic acid and Bacterial Disease
| Article | Year |
|---|---|
Pyridonecarboxylic acids as antibacterial agents. 2. Synthesis and structure-activity relationships of 1,6,7-trisubstituted 1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids, including enoxacin, a new antibacterial agent.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Enoxacin; Escherichia coli; Mice; Naphthyridin | 1984 |
Activity of AT-2266 compared with those of norfloxacin, pipemidic acid, nalidixic acid, and gentamicin against various experimental infections in mice.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Enoxacin; Gentamicins; Male; Mice; Nalidixic A | 1983 |
In vitro and in vivo antibacterial activity of AT-2266.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Enoxacin | 1983 |
Comparative activities of AM-715 and pipemidic and nalidixic acids against experimentally induced systemic and urinary tract infections.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Mice; Nalidixic Acid; Nicotinic Acids; Norflox | 1981 |
[Clinical results of the use of pipemidic acid in the common urinary tract infections].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Female; Humans; Male; Middle Aged; Nicotinic Acids; P | 1980 |
[Pipemidic acid in urinary tract infections in aged patients].
Topics: Age Factors; Aged; Bacterial Infections; Female; Humans; Male; Middle Aged; Nicotinic Acids; Pipemid | 1980 |
[Significance and importance of the use of pipemidic acid in the therapy of acute and chronic urinary tract infections].
Topics: Acute Disease; Adult; Bacteria; Bacterial Infections; Chronic Disease; Female; Humans; Male; Microbi | 1980 |
[Pipemidic acid levels in prostatic tissue in man. Preliminary results (proceedings)].
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Bacterial Infections; Humans; Male; Middle Aged; Nicoti | 1979 |
[Use of pipemidic acid in the treatment of urinary tract infections].
Topics: Adult; Aged; Bacterial Infections; Cystitis; Female; Humans; Male; Middle Aged; Nalidixic Acid; Nico | 1979 |
[The treatment of bacterial colpitis with the preparation Palin].
Topics: Adolescent; Adult; Bacterial Infections; Drug Evaluation; Drug Tolerance; Female; Humans; Middle Age | 1990 |
Treatment of experimental cystitis in the rat with a single dose of fosfomycin trometamol.
Topics: Administration, Oral; Animals; Bacterial Infections; Cystitis; Drug Combinations; Fosfomycin; Norflo | 1988 |
In vitro and in vivo activity of NY-198, a new difluorinated quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Male; Mice; Microbial Sensit | 1987 |
Antimicrobial activity of norfloxacin in enteric and urinary tract infections: combined effect of norfloxacin with aminoglycosides, tetracycline and chloramphenicol.
Topics: Acinetobacter; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Chloramphenicol; Drug C | 1986 |