pipecolic acid has been researched along with Syndrome in 15 studies
pipecolic acid: RN given refers to cpd without isomeric designation
pipecolic acid : A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.
pipecolate : A piperidinecarboxylate that is the conjugate base of pipecolic acid.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A child with the Dyggve-Melchior-Clausen syndrome associated with elevated pipecolic acid levels in plasma and urine is described." | 7.68 | Dyggve-Melchior-Clausen syndrome with increased pipecolic acid in plasma and urine. ( Carroll, JE; Hahn, DA; Rizzo, WB; Roesel, RA; van der Zalm, T, 1991) |
| "Serum pipecolic acid was measured in patients with neonatal adrenoleukodystrophy (NALD), sex-linked ALD, and the cerebrohepatorenal syndrome of Zellweger." | 7.67 | Hyperpipecolic acidemia in neonatal adrenoleukodystrophy. ( Kelley, RI; Moser, HW, 1984) |
| "Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease patients can be divided into at least five distinct groups, according to the nature of their plasma changes and their fibroblast phytanic acid oxidase activities." | 7.67 | Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase. ( Danks, DM; Fellenberg, AJ; Poulos, A; Sharp, P, 1985) |
| "A child with the Dyggve-Melchior-Clausen syndrome associated with elevated pipecolic acid levels in plasma and urine is described." | 3.68 | Dyggve-Melchior-Clausen syndrome with increased pipecolic acid in plasma and urine. ( Carroll, JE; Hahn, DA; Rizzo, WB; Roesel, RA; van der Zalm, T, 1991) |
| "Serum pipecolic acid was measured in patients with neonatal adrenoleukodystrophy (NALD), sex-linked ALD, and the cerebrohepatorenal syndrome of Zellweger." | 3.67 | Hyperpipecolic acidemia in neonatal adrenoleukodystrophy. ( Kelley, RI; Moser, HW, 1984) |
| "Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease patients can be divided into at least five distinct groups, according to the nature of their plasma changes and their fibroblast phytanic acid oxidase activities." | 3.67 | Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase. ( Danks, DM; Fellenberg, AJ; Poulos, A; Sharp, P, 1985) |
| "Purified rat peroxisomes have been reported to oxidize D-pipecolic acid and the pipecolaturia of Zellweger syndrome has been attributed to the absence of peroxisomes." | 3.67 | L-pipecolaturia in Zellweger syndrome. ( Dancis, J; Hutzler, J; Lam, S, 1986) |
| "The plasma pipecolic acid concentration in two newborn infants with Zellweger syndrome at ages 4 and 10 days were 7." | 3.67 | The significance of hyperpipecolatemia in Zellweger syndrome. ( Dancis, J; Hutzler, J, 1986) |
| " In early life the diagnosis of Zellweger (cerebro-hepato-renal) syndrome was considered because of hypotonia, craniofacial dysmorphia, abnormal liver functions and pipecolic aciduria." | 3.67 | Long term survival of a patient with the cerebro-hepato-renal (Zellweger) syndrome. ( Bleeker-Wagemakers, EM; Oorthuys, JW; Schutgens, RB; Wanders, RJ, 1986) |
| "As Zellweger syndrome is usually fatal in early life, prenatal diagnosis of the disease is important." | 2.37 | Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment. ( Heymans, HS; Schrakamp, G; Schram, AW; Schutgens, RB; Tager, JM; van den Bosch, H; Wanders, RJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kelley, RI | 1 |
| Moser, HW | 3 |
| Govaerts, L | 1 |
| Monnens, L | 2 |
| Tegelaers, W | 1 |
| Trijbels, F | 1 |
| van Raay-Selten, A | 1 |
| Roesel, RA | 1 |
| Carroll, JE | 1 |
| Rizzo, WB | 1 |
| van der Zalm, T | 1 |
| Hahn, DA | 1 |
| Poulos, A | 1 |
| Sharp, P | 1 |
| Fellenberg, AJ | 1 |
| Danks, DM | 1 |
| Heymans, H | 1 |
| Lam, S | 1 |
| Hutzler, J | 2 |
| Dancis, J | 2 |
| Trijbels, JM | 2 |
| Monnens, LA | 2 |
| Melis, G | 1 |
| van den Broekvan Essen, M | 1 |
| Bruckwilder, M | 1 |
| Schutgens, RB | 4 |
| Wanders, RJ | 3 |
| Heymans, HS | 3 |
| Schram, AW | 1 |
| Tager, JM | 1 |
| Schrakamp, G | 1 |
| van den Bosch, H | 1 |
| Barth, PG | 2 |
| Moser, AE | 1 |
| Bleeker-Wagemakers, EM | 2 |
| Jansonius-Schultheiss, K | 1 |
| Derix, M | 1 |
| Nelck, GF | 1 |
| Lazarow, PB | 1 |
| Fujiki, Y | 1 |
| Small, GM | 1 |
| Watkins, P | 1 |
| Moser, H | 1 |
| van den Berg, GA | 1 |
| Breukelman, H | 1 |
| Elzinga, H | 1 |
| Muskiet, FA | 1 |
| Oorthuys, JW | 1 |
| Bakkeren, JA | 1 |
| Dingemans, KP | 1 |
| Douwes, AC | 1 |
| van der Klei-van Moorsel, JM | 1 |
2 reviews available for pipecolic acid and Syndrome
| Article | Year |
|---|---|
Peroxisomal disorders: clinical characterization.
Topics: Adrenoleukodystrophy; Brain Diseases; Chondrodysplasia Punctata; Enzymes; Humans; Hyperoxaluria, Pri | 1987 |
Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment.
Topics: Bile Acids and Salts; Brain Diseases; Catalase; Enzymes; Fatty Acids; Humans; Kidney Diseases; Liver | 1987 |
13 other studies available for pipecolic acid and Syndrome
| Article | Year |
|---|---|
Hyperpipecolic acidemia in neonatal adrenoleukodystrophy.
Topics: Abnormalities, Multiple; Adrenoleukodystrophy; Brain; Child; Child, Preschool; Diffuse Cerebral Scle | 1984 |
Cerebro-hepato-renal syndrome of Zellweger: clinical symptoms and relevant laboratory findings in 16 patients.
Topics: Bile Acids and Salts; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Metabolism, I | 1982 |
Dyggve-Melchior-Clausen syndrome with increased pipecolic acid in plasma and urine.
Topics: Bone Diseases, Developmental; Child; Dwarfism; Fatty Acids; Fibroblasts; Humans; Intellectual Disabi | 1991 |
Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase.
Topics: Adrenoleukodystrophy; Brain Diseases; Cells, Cultured; Child, Preschool; Chromatography, Gas; Diffus | 1985 |
Peroxisomal disorders.
Topics: Adrenoleukodystrophy; Animals; Brain Diseases; Child; Child, Preschool; Chondrodysplasia Punctata; H | 1986 |
L-pipecolaturia in Zellweger syndrome.
Topics: Brain Diseases; D-Amino-Acid Oxidase; Humans; Kidney Diseases; Liver Diseases; Pipecolic Acids; Ster | 1986 |
The significance of hyperpipecolatemia in Zellweger syndrome.
Topics: Abnormalities, Multiple; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Humans; Infant; Infan | 1986 |
Localization of pipecolic acid metabolism in rat liver peroxisomes: probable explanation for hyperpipecolataemia in Zellweger syndrome.
Topics: Animals; Brain Diseases; Humans; In Vitro Techniques; Kidney Diseases; Liver; Liver Diseases; Metabo | 1987 |
A sibship with a mild variant of Zellweger syndrome.
Topics: Acyltransferases; Bile Acids and Salts; Brain Diseases; Child; Child, Preschool; Fatty Acids; Female | 1987 |
Presence of the peroxisomal 22-kDa integral membrane protein in the liver of a person lacking recognizable peroxisomes (Zellweger syndrome).
Topics: Catalase; Cell Compartmentation; Cholestanols; Facial Bones; Fatty Acids; Female; Humans; Immunosorb | 1986 |
Determination of pipecolic acid in urine and plasma by isotope dilution mass fragmentography.
Topics: Abnormalities, Multiple; Adolescent; Child; Child, Preschool; Deuterium; Gas Chromatography-Mass Spe | 1986 |
Long term survival of a patient with the cerebro-hepato-renal (Zellweger) syndrome.
Topics: Abnormalities, Multiple; Acyltransferases; Brain Diseases; Facial Bones; Fatty Acids; Female; Fibrob | 1986 |
A milder variant of Zellweger syndrome.
Topics: Abnormalities, Multiple; Biopsy; Child, Preschool; Choroid; Epilepsy; Facial Bones; Genes, Recessive | 1985 |