pipecolic acid has been researched along with Metabolism, Inborn Errors in 12 studies
pipecolic acid: RN given refers to cpd without isomeric designation
pipecolic acid : A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.
pipecolate : A piperidinecarboxylate that is the conjugate base of pipecolic acid.
Metabolism, Inborn Errors: Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Elevated concentrations of pipecolic acid have been reported in plasma and CSF of patients with pyridoxine-dependent epilepsy, but its molecular background is unclear." | 3.73 | Pipecolic acid concentrations in brain tissue of nutritionally pyridoxine-deficient rats. ( Hoeger, H; Jakobs, C; Leschnik, M; Muehl, A; Plecko, B; Stoeckler-Ipsiroglu, S; Stromberger, C; Struys, E, 2005) |
| "As Zellweger syndrome is usually fatal in early life, prenatal diagnosis of the disease is important." | 2.37 | Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment. ( Heymans, HS; Schrakamp, G; Schram, AW; Schutgens, RB; Tager, JM; van den Bosch, H; Wanders, RJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Mathis, D | 1 |
| Beese, K | 1 |
| Rüegg, C | 1 |
| Plecko, B | 2 |
| Hersberger, M | 1 |
| Baas, JC | 1 |
| van de Laar, R | 1 |
| Dorland, L | 1 |
| Duran, M | 1 |
| Berger, R | 1 |
| Poll-The, BT | 2 |
| de Koning, TJ | 1 |
| Hoeger, H | 1 |
| Jakobs, C | 2 |
| Struys, E | 1 |
| Stromberger, C | 1 |
| Leschnik, M | 1 |
| Muehl, A | 1 |
| Stoeckler-Ipsiroglu, S | 1 |
| Govaerts, L | 1 |
| Monnens, L | 2 |
| Tegelaers, W | 1 |
| Trijbels, F | 1 |
| van Raay-Selten, A | 1 |
| Espeel, M | 1 |
| Mandel, H | 1 |
| Poggi, F | 1 |
| Smeitink, JA | 1 |
| Wanders, RJ | 3 |
| Kerckaert, I | 1 |
| Schutgens, RB | 3 |
| Saudubray, JM | 1 |
| Roels, F | 1 |
| Armstrong, DW | 1 |
| Zukowski, J | 1 |
| Ercal, N | 1 |
| Gasper, M | 1 |
| Zee, T | 1 |
| Stellaard, F | 1 |
| Caruso, U | 1 |
| Romano, C | 1 |
| Heymans, H | 1 |
| Trijbels, JM | 1 |
| Monnens, LA | 1 |
| Melis, G | 1 |
| van den Broekvan Essen, M | 1 |
| Bruckwilder, M | 1 |
| Heymans, HS | 2 |
| Schram, AW | 1 |
| Tager, JM | 1 |
| Schrakamp, G | 1 |
| van den Bosch, H | 1 |
| Barth, PG | 1 |
| Moser, AE | 1 |
| Moser, HW | 1 |
| Bleeker-Wagemakers, EM | 1 |
| Jansonius-Schultheiss, K | 1 |
| Derix, M | 1 |
| Nelck, GF | 1 |
2 reviews available for pipecolic acid and Metabolism, Inborn Errors
| Article | Year |
|---|---|
Peroxisomal disorders: clinical characterization.
Topics: Adrenoleukodystrophy; Brain Diseases; Chondrodysplasia Punctata; Enzymes; Humans; Hyperoxaluria, Pri | 1987 |
Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment.
Topics: Bile Acids and Salts; Brain Diseases; Catalase; Enzymes; Fatty Acids; Humans; Kidney Diseases; Liver | 1987 |
10 other studies available for pipecolic acid and Metabolism, Inborn Errors
| Article | Year |
|---|---|
LC-MS/MS method for the differential diagnosis of treatable early onset inherited metabolic epilepsies.
Topics: Aldehyde Dehydrogenase; Biomarkers; Chromatography, Liquid; Diagnosis, Differential; Epilepsy; Human | 2020 |
Plasma pipecolic acid is frequently elevated in non-peroxisomal disease.
Topics: Biomarkers; False Positive Reactions; Humans; Metabolism, Inborn Errors; Peroxisomal Disorders; Pipe | 2002 |
Pipecolic acid concentrations in brain tissue of nutritionally pyridoxine-deficient rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Brain; Disease Models, Animal; Epilepsy; Female | 2005 |
Cerebro-hepato-renal syndrome of Zellweger: clinical symptoms and relevant laboratory findings in 16 patients.
Topics: Bile Acids and Salts; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Metabolism, I | 1982 |
Peroxisome mosaicism in the livers of peroxisomal deficiency patients.
Topics: Bile Acids and Salts; Catalase; Child; Child, Preschool; Fatty Acids; Fibroblasts; Humans; Immunoblo | 1995 |
Stereochemistry of pipecolic acid found in the urine and plasma of subjects with peroxisomal deficiencies.
Topics: Adult; Aged; Aged, 80 and over; Chromatography; Humans; Infant; Metabolism, Inborn Errors; Microbodi | 1993 |
Analysis of pipecolic acid in biological fluids using capillary gas chromatography with electron-capture detection and [2H11]pipecolic acid as internal standard.
Topics: Body Fluids; Chromatography, Gas; Electrons; Humans; Metabolism, Inborn Errors; Microbodies; Pipecol | 1992 |
[Diagnostic approach to peroxisomal diseases].
Topics: Bile Acids and Salts; Diagnosis, Differential; Fatty Acids; Humans; Infant, Newborn; Metabolism, Inb | 1991 |
Localization of pipecolic acid metabolism in rat liver peroxisomes: probable explanation for hyperpipecolataemia in Zellweger syndrome.
Topics: Animals; Brain Diseases; Humans; In Vitro Techniques; Kidney Diseases; Liver; Liver Diseases; Metabo | 1987 |
A sibship with a mild variant of Zellweger syndrome.
Topics: Acyltransferases; Bile Acids and Salts; Brain Diseases; Child; Child, Preschool; Fatty Acids; Female | 1987 |