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pipecolic acid and Liver Dysfunction

pipecolic acid has been researched along with Liver Dysfunction in 11 studies

pipecolic acid: RN given refers to cpd without isomeric designation
pipecolic acid : A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.
pipecolate : A piperidinecarboxylate that is the conjugate base of pipecolic acid.

Research Excerpts

ExcerptRelevanceReference
"Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease patients can be divided into at least five distinct groups, according to the nature of their plasma changes and their fibroblast phytanic acid oxidase activities."7.67Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase. ( Danks, DM; Fellenberg, AJ; Poulos, A; Sharp, P, 1985)
"Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease patients can be divided into at least five distinct groups, according to the nature of their plasma changes and their fibroblast phytanic acid oxidase activities."3.67Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase. ( Danks, DM; Fellenberg, AJ; Poulos, A; Sharp, P, 1985)
"Purified rat peroxisomes have been reported to oxidize D-pipecolic acid and the pipecolaturia of Zellweger syndrome has been attributed to the absence of peroxisomes."3.67L-pipecolaturia in Zellweger syndrome. ( Dancis, J; Hutzler, J; Lam, S, 1986)
"The plasma pipecolic acid concentration in two newborn infants with Zellweger syndrome at ages 4 and 10 days were 7."3.67The significance of hyperpipecolatemia in Zellweger syndrome. ( Dancis, J; Hutzler, J, 1986)
" In early life the diagnosis of Zellweger (cerebro-hepato-renal) syndrome was considered because of hypotonia, craniofacial dysmorphia, abnormal liver functions and pipecolic aciduria."3.67Long term survival of a patient with the cerebro-hepato-renal (Zellweger) syndrome. ( Bleeker-Wagemakers, EM; Oorthuys, JW; Schutgens, RB; Wanders, RJ, 1986)
"As Zellweger syndrome is usually fatal in early life, prenatal diagnosis of the disease is important."2.37Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment. ( Heymans, HS; Schrakamp, G; Schram, AW; Schutgens, RB; Tager, JM; van den Bosch, H; Wanders, RJ, 1987)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stefan, RI1
Nejem, RM1
van Staden, JF1
Aboul-Enein, HY1
Hutzler, J3
Dancis, J3
Poulos, A1
Sharp, P1
Fellenberg, AJ1
Danks, DM1
Moser, HW2
Monnens, L1
Heymans, H1
Lam, S1
Trijbels, JM1
Monnens, LA1
Melis, G1
van den Broekvan Essen, M1
Bruckwilder, M1
Schutgens, RB3
Wanders, RJ3
Heymans, HS2
Schram, AW1
Tager, JM1
Schrakamp, G1
van den Bosch, H1
Barth, PG1
Moser, AE1
Bleeker-Wagemakers, EM2
Jansonius-Schultheiss, K1
Derix, M1
Nelck, GF1
Oorthuys, JW1

Reviews

2 reviews available for pipecolic acid and Liver Dysfunction

ArticleYear
Peroxisomal disorders: clinical characterization.
    Journal of inherited metabolic disease, 1987, Volume: 10 Suppl 1

    Topics: Adrenoleukodystrophy; Brain Diseases; Chondrodysplasia Punctata; Enzymes; Humans; Hyperoxaluria, Pri

1987
Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment.
    Journal of inherited metabolic disease, 1987, Volume: 10 Suppl 1

    Topics: Bile Acids and Salts; Brain Diseases; Catalase; Enzymes; Fatty Acids; Humans; Kidney Diseases; Liver

1987

Other Studies

9 other studies available for pipecolic acid and Liver Dysfunction

ArticleYear
New amperometric biosensors based on diamond paste for the assay of L- and D-pipecolic acids in serum samples.
    Preparative biochemistry & biotechnology, 2004, Volume: 34, Issue:2

    Topics: Amino Acid Oxidoreductases; Biomarkers; Biosensing Techniques; Diamond; Electrochemistry; Electrodes

2004
The determination of pipecolic acid: method and results of hospital survey.
    Clinica chimica acta; international journal of clinical chemistry, 1983, Feb-28, Volume: 128, Issue:1

    Topics: Amino Acids; Autoanalysis; Child; Child, Preschool; Humans; Hydroxyproline; Indicators and Reagents;

1983
Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase.
    Human genetics, 1985, Volume: 70, Issue:2

    Topics: Adrenoleukodystrophy; Brain Diseases; Cells, Cultured; Child, Preschool; Chromatography, Gas; Diffus

1985
Peroxisomal disorders.
    The Journal of pediatrics, 1986, Volume: 108, Issue:1

    Topics: Adrenoleukodystrophy; Animals; Brain Diseases; Child; Child, Preschool; Chondrodysplasia Punctata; H

1986
L-pipecolaturia in Zellweger syndrome.
    Biochimica et biophysica acta, 1986, Jun-19, Volume: 882, Issue:2

    Topics: Brain Diseases; D-Amino-Acid Oxidase; Humans; Kidney Diseases; Liver Diseases; Pipecolic Acids; Ster

1986
The significance of hyperpipecolatemia in Zellweger syndrome.
    American journal of human genetics, 1986, Volume: 38, Issue:5

    Topics: Abnormalities, Multiple; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Humans; Infant; Infan

1986
Localization of pipecolic acid metabolism in rat liver peroxisomes: probable explanation for hyperpipecolataemia in Zellweger syndrome.
    Journal of inherited metabolic disease, 1987, Volume: 10, Issue:2

    Topics: Animals; Brain Diseases; Humans; In Vitro Techniques; Kidney Diseases; Liver; Liver Diseases; Metabo

1987
A sibship with a mild variant of Zellweger syndrome.
    Journal of inherited metabolic disease, 1987, Volume: 10, Issue:3

    Topics: Acyltransferases; Bile Acids and Salts; Brain Diseases; Child; Child, Preschool; Fatty Acids; Female

1987
Long term survival of a patient with the cerebro-hepato-renal (Zellweger) syndrome.
    Clinical genetics, 1986, Volume: 29, Issue:2

    Topics: Abnormalities, Multiple; Acyltransferases; Brain Diseases; Facial Bones; Fatty Acids; Female; Fibrob

1986