pipecolic acid has been researched along with Intellectual Disability in 3 studies
pipecolic acid: RN given refers to cpd without isomeric designation
pipecolic acid : A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.
pipecolate : A piperidinecarboxylate that is the conjugate base of pipecolic acid.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A child with the Dyggve-Melchior-Clausen syndrome associated with elevated pipecolic acid levels in plasma and urine is described." | 7.68 | Dyggve-Melchior-Clausen syndrome with increased pipecolic acid in plasma and urine. ( Carroll, JE; Hahn, DA; Rizzo, WB; Roesel, RA; van der Zalm, T, 1991) |
| "A child with the Dyggve-Melchior-Clausen syndrome associated with elevated pipecolic acid levels in plasma and urine is described." | 3.68 | Dyggve-Melchior-Clausen syndrome with increased pipecolic acid in plasma and urine. ( Carroll, JE; Hahn, DA; Rizzo, WB; Roesel, RA; van der Zalm, T, 1991) |
| " In early life the diagnosis of Zellweger (cerebro-hepato-renal) syndrome was considered because of hypotonia, craniofacial dysmorphia, abnormal liver functions and pipecolic aciduria." | 3.67 | Long term survival of a patient with the cerebro-hepato-renal (Zellweger) syndrome. ( Bleeker-Wagemakers, EM; Oorthuys, JW; Schutgens, RB; Wanders, RJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roesel, RA | 1 |
| Carroll, JE | 1 |
| Rizzo, WB | 1 |
| van der Zalm, T | 1 |
| Hahn, DA | 1 |
| Bleeker-Wagemakers, EM | 1 |
| Oorthuys, JW | 1 |
| Wanders, RJ | 1 |
| Schutgens, RB | 2 |
| Barth, PG | 1 |
| Bakkeren, JA | 1 |
| Dingemans, KP | 1 |
| Heymans, HS | 1 |
| Douwes, AC | 1 |
| van der Klei-van Moorsel, JM | 1 |
3 other studies available for pipecolic acid and Intellectual Disability
| Article | Year |
|---|---|
Dyggve-Melchior-Clausen syndrome with increased pipecolic acid in plasma and urine.
Topics: Bone Diseases, Developmental; Child; Dwarfism; Fatty Acids; Fibroblasts; Humans; Intellectual Disabi | 1991 |
Long term survival of a patient with the cerebro-hepato-renal (Zellweger) syndrome.
Topics: Abnormalities, Multiple; Acyltransferases; Brain Diseases; Facial Bones; Fatty Acids; Female; Fibrob | 1986 |
A milder variant of Zellweger syndrome.
Topics: Abnormalities, Multiple; Biopsy; Child, Preschool; Choroid; Epilepsy; Facial Bones; Genes, Recessive | 1985 |