pipecolic acid has been researched along with Brain Disorders in 10 studies
pipecolic acid: RN given refers to cpd without isomeric designation
pipecolic acid : A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.
pipecolate : A piperidinecarboxylate that is the conjugate base of pipecolic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease patients can be divided into at least five distinct groups, according to the nature of their plasma changes and their fibroblast phytanic acid oxidase activities." | 7.67 | Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase. ( Danks, DM; Fellenberg, AJ; Poulos, A; Sharp, P, 1985) |
| "We explored a metabolic etiology of cerebral malaria (CM) coma." | 5.72 | Pipecolic Acid, a Putative Mediator of the Encephalopathy of Cerebral Malaria and the Experimental Model of Cerebral Malaria. ( Daily, JP; Fazzari, M; Keswani, T; Nieves, E; Obeidallah, A; Seydel, K; Sidoli, S; Taylor, T, 2022) |
| "Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease patients can be divided into at least five distinct groups, according to the nature of their plasma changes and their fibroblast phytanic acid oxidase activities." | 3.67 | Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase. ( Danks, DM; Fellenberg, AJ; Poulos, A; Sharp, P, 1985) |
| "Purified rat peroxisomes have been reported to oxidize D-pipecolic acid and the pipecolaturia of Zellweger syndrome has been attributed to the absence of peroxisomes." | 3.67 | L-pipecolaturia in Zellweger syndrome. ( Dancis, J; Hutzler, J; Lam, S, 1986) |
| "The plasma pipecolic acid concentration in two newborn infants with Zellweger syndrome at ages 4 and 10 days were 7." | 3.67 | The significance of hyperpipecolatemia in Zellweger syndrome. ( Dancis, J; Hutzler, J, 1986) |
| " In early life the diagnosis of Zellweger (cerebro-hepato-renal) syndrome was considered because of hypotonia, craniofacial dysmorphia, abnormal liver functions and pipecolic aciduria." | 3.67 | Long term survival of a patient with the cerebro-hepato-renal (Zellweger) syndrome. ( Bleeker-Wagemakers, EM; Oorthuys, JW; Schutgens, RB; Wanders, RJ, 1986) |
| "As Zellweger syndrome is usually fatal in early life, prenatal diagnosis of the disease is important." | 2.37 | Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment. ( Heymans, HS; Schrakamp, G; Schram, AW; Schutgens, RB; Tager, JM; van den Bosch, H; Wanders, RJ, 1987) |
| "We explored a metabolic etiology of cerebral malaria (CM) coma." | 1.72 | Pipecolic Acid, a Putative Mediator of the Encephalopathy of Cerebral Malaria and the Experimental Model of Cerebral Malaria. ( Daily, JP; Fazzari, M; Keswani, T; Nieves, E; Obeidallah, A; Seydel, K; Sidoli, S; Taylor, T, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keswani, T | 1 |
| Obeidallah, A | 1 |
| Nieves, E | 1 |
| Sidoli, S | 1 |
| Fazzari, M | 1 |
| Taylor, T | 1 |
| Seydel, K | 1 |
| Daily, JP | 1 |
| Poulos, A | 1 |
| Sharp, P | 1 |
| Fellenberg, AJ | 1 |
| Danks, DM | 1 |
| Moser, HW | 2 |
| Monnens, L | 1 |
| Heymans, H | 1 |
| Lam, S | 1 |
| Hutzler, J | 2 |
| Dancis, J | 2 |
| Trijbels, JM | 1 |
| Monnens, LA | 1 |
| Melis, G | 1 |
| van den Broekvan Essen, M | 1 |
| Bruckwilder, M | 1 |
| Schutgens, RB | 3 |
| Wanders, RJ | 3 |
| Heymans, HS | 2 |
| Schram, AW | 1 |
| Tager, JM | 1 |
| Schrakamp, G | 1 |
| van den Bosch, H | 1 |
| Barth, PG | 1 |
| Moser, AE | 1 |
| Bleeker-Wagemakers, EM | 2 |
| Jansonius-Schultheiss, K | 1 |
| Derix, M | 1 |
| Nelck, GF | 1 |
| Oorthuys, JW | 1 |
2 reviews available for pipecolic acid and Brain Disorders
| Article | Year |
|---|---|
Peroxisomal disorders: clinical characterization.
Topics: Adrenoleukodystrophy; Brain Diseases; Chondrodysplasia Punctata; Enzymes; Humans; Hyperoxaluria, Pri | 1987 |
Zellweger syndrome: biochemical procedures in diagnosis, prevention and treatment.
Topics: Bile Acids and Salts; Brain Diseases; Catalase; Enzymes; Fatty Acids; Humans; Kidney Diseases; Liver | 1987 |
8 other studies available for pipecolic acid and Brain Disorders
| Article | Year |
|---|---|
Pipecolic Acid, a Putative Mediator of the Encephalopathy of Cerebral Malaria and the Experimental Model of Cerebral Malaria.
Topics: Animals; Brain; Brain Diseases; Coma; Disease Models, Animal; Humans; Malaria, Cerebral; Mice; Mice, | 2022 |
Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: plasma changes and skin fibroblast phytanic acid oxidase.
Topics: Adrenoleukodystrophy; Brain Diseases; Cells, Cultured; Child, Preschool; Chromatography, Gas; Diffus | 1985 |
Peroxisomal disorders.
Topics: Adrenoleukodystrophy; Animals; Brain Diseases; Child; Child, Preschool; Chondrodysplasia Punctata; H | 1986 |
L-pipecolaturia in Zellweger syndrome.
Topics: Brain Diseases; D-Amino-Acid Oxidase; Humans; Kidney Diseases; Liver Diseases; Pipecolic Acids; Ster | 1986 |
The significance of hyperpipecolatemia in Zellweger syndrome.
Topics: Abnormalities, Multiple; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Humans; Infant; Infan | 1986 |
Localization of pipecolic acid metabolism in rat liver peroxisomes: probable explanation for hyperpipecolataemia in Zellweger syndrome.
Topics: Animals; Brain Diseases; Humans; In Vitro Techniques; Kidney Diseases; Liver; Liver Diseases; Metabo | 1987 |
A sibship with a mild variant of Zellweger syndrome.
Topics: Acyltransferases; Bile Acids and Salts; Brain Diseases; Child; Child, Preschool; Fatty Acids; Female | 1987 |
Long term survival of a patient with the cerebro-hepato-renal (Zellweger) syndrome.
Topics: Abnormalities, Multiple; Acyltransferases; Brain Diseases; Facial Bones; Fatty Acids; Female; Fibrob | 1986 |