pioglitazone has been researched along with Ventricular Fibrillation in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated whether TZDs affect onset, spectral characteristics, and mortality of ischemic ventricular fibrillation (VF) and whether such effects are recapitulated by a non-selective K(ATP) blocker (glyburide) or a mitochondrial K(ATP) blocker (5-hydroxydecanoate)." | 3.78 | Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs. ( Greyson, CR; Lu, L; Reiter, MJ; Sarraf, M; Schwartz, GG; Ye, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morrow, JP | 1 |
| Katchman, A | 1 |
| Son, NH | 1 |
| Trent, CM | 1 |
| Khan, R | 1 |
| Shiomi, T | 1 |
| Huang, H | 1 |
| Amin, V | 1 |
| Lader, JM | 1 |
| Vasquez, C | 1 |
| Morley, GE | 1 |
| D'Armiento, J | 1 |
| Homma, S | 1 |
| Goldberg, IJ | 1 |
| Marx, SO | 1 |
| Sarraf, M | 1 |
| Lu, L | 2 |
| Ye, S | 1 |
| Reiter, MJ | 2 |
| Greyson, CR | 2 |
| Schwartz, GG | 2 |
| Xu, Y | 1 |
| Chicco, A | 1 |
3 other studies available for pioglitazone and Ventricular Fibrillation
| Article | Year |
|---|---|
Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias.
Topics: Action Potentials; Animals; Calcium; Connexin 43; Death, Sudden, Cardiac; Disease Models, Animal; El | 2011 |
Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Vessels; Death, Sudden, Cardiac; Decanoic Acids; Female; G | 2012 |
Thiazolidinedione drugs block cardiac KATP channels and may increase propensity for ischaemic ventricular fibrillation in pigs.
Topics: Animals; Blood Pressure; Disease Models, Animal; Heart; KATP Channels; Pioglitazone; Rosiglitazone; | 2008 |