pioglitazone has been researched along with Retinoblastoma in 1 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to study the antitumor effects of the PPARγ agonist pioglitazone on human retinoblastoma." | 7.85 | Pioglitazone inhibits growth of human retinoblastoma cells via regulation of NF-κB inflammation signals. ( Bi, Z; Liu, Y; Wang, F, 2017) |
| "We aimed to study the antitumor effects of the PPARγ agonist pioglitazone on human retinoblastoma." | 3.85 | Pioglitazone inhibits growth of human retinoblastoma cells via regulation of NF-κB inflammation signals. ( Bi, Z; Liu, Y; Wang, F, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, F | 1 |
| Liu, Y | 1 |
| Bi, Z | 1 |
1 other study available for pioglitazone and Retinoblastoma
| Article | Year |
|---|---|
Pioglitazone inhibits growth of human retinoblastoma cells via regulation of NF-κB inflammation signals.
Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Gene Expression Regulation, Neoplastic; H | 2017 |