pioglitazone has been researched along with Renal Insufficiency in 4 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with fenofibrate and pioglitazone either alone or in combination markedly attenuated DOX-induced injury by suppression of oxidative stress, inflammation and apoptosis." | 1.91 | Impact of peroxisome proliferator activated receptor agonist drugs in a model of nephrotoxicity in rats. ( Ali, AA; El-Raouf, OMA; El-Rhman, RHA; Gad, AM; Saad, EB, 2023) |
| "Cisplatin is a chemotherapeutic agent, which is used in the treatment of various solid organ cancers, and its main dose limiting side effect of cisplatin is nephrotoxicity." | 1.40 | Effect of creatine and pioglitazone on Hk-2 cell line cisplatin nephrotoxicity. ( Bedir, A; Genc, G; Kilinc, V; Ozkaya, O, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kökény, G | 1 |
| Calvier, L | 1 |
| Hansmann, G | 1 |
| Ali, AA | 1 |
| Saad, EB | 1 |
| El-Rhman, RHA | 1 |
| El-Raouf, OMA | 1 |
| Gad, AM | 1 |
| Genc, G | 1 |
| Kilinc, V | 1 |
| Bedir, A | 1 |
| Ozkaya, O | 1 |
| Phillips, P | 1 |
| Braddon, J | 1 |
2 reviews available for pioglitazone and Renal Insufficiency
| Article | Year |
|---|---|
PPARγ and TGFβ-Major Regulators of Metabolism, Inflammation, and Fibrosis in the Lungs and Kidneys.
Topics: Animals; Humans; Kidney; Lung; Pioglitazone; PPAR gamma; Pulmonary Arterial Hypertension; Pulmonary | 2021 |
Oral hypoglycaemics. When not to use what.
Topics: Acarbose; Acidosis, Lactic; Aged; Contraindications; Diabetes Mellitus, Type 2; Female; Glyburide; H | 2002 |
2 other studies available for pioglitazone and Renal Insufficiency
| Article | Year |
|---|---|
Impact of peroxisome proliferator activated receptor agonist drugs in a model of nephrotoxicity in rats.
Topics: Animals; Apoptosis; Doxorubicin; Fenofibrate; Hypoglycemic Agents; Kidney; Male; NF-kappa B; Oxidati | 2023 |
Effect of creatine and pioglitazone on Hk-2 cell line cisplatin nephrotoxicity.
Topics: Antineoplastic Agents; Cell Line; Cisplatin; Creatine; Drug Evaluation, Preclinical; Humans; Hypogly | 2014 |