Page last updated: 2024-11-02

pioglitazone and Pulmonary Hypertension

pioglitazone has been researched along with Pulmonary Hypertension in 4 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
"Pioglitazone treatment increased oxygen saturation and pTyr14cav-1 vs."5.72Pioglitazone restores phosphorylation of downregulated caveolin-1 in right ventricle of monocrotaline-induced pulmonary hypertension. ( Balis, P; Doka, G; Klimas, J; Kmecova, Z; Krenek, P; Malikova, E; Pivackova, LB; Trubacova, S; Velasova, E, 2022)
"Pioglitazone treatment increased oxygen saturation and pTyr14cav-1 vs."1.72Pioglitazone restores phosphorylation of downregulated caveolin-1 in right ventricle of monocrotaline-induced pulmonary hypertension. ( Balis, P; Doka, G; Klimas, J; Kmecova, Z; Krenek, P; Malikova, E; Pivackova, LB; Trubacova, S; Velasova, E, 2022)
"Pioglitazone treatment improved survival, reduced PASP, muscularization of small pulmonary arteries, and medial wall thickness."1.43Pioglitazone alleviates cardiac and vascular remodelling and improves survival in monocrotaline induced pulmonary arterial hypertension. ( Baldus, S; Behringer, A; Berghausen, EM; Blaschke, F; Caglayan, E; Er, F; Gassanov, N; Kappert, K; Odenthal, M; Rosenkranz, S; Ten Freyhaus, H; Trappiel, M; Wellnhofer, E, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Malikova, E1
Kmecova, Z1
Doka, G1
Pivackova, LB1
Balis, P1
Trubacova, S1
Velasova, E1
Krenek, P1
Klimas, J1
Legchenko, E1
Chouvarine, P1
Borchert, P1
Fernandez-Gonzalez, A1
Snay, E1
Meier, M1
Maegel, L1
Mitsialis, SA1
Rog-Zielinska, EA1
Kourembanas, S1
Jonigk, D1
Hansmann, G1
Lim, GB1
Behringer, A1
Trappiel, M1
Berghausen, EM1
Ten Freyhaus, H1
Wellnhofer, E1
Odenthal, M1
Blaschke, F1
Er, F1
Gassanov, N1
Rosenkranz, S1
Baldus, S1
Kappert, K1
Caglayan, E1

Other Studies

4 other studies available for pioglitazone and Pulmonary Hypertension

ArticleYear
Pioglitazone restores phosphorylation of downregulated caveolin-1 in right ventricle of monocrotaline-induced pulmonary hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2022, Feb-17, Volume: 44, Issue:2

    Topics: Animals; Caveolin 1; Disease Models, Animal; Heart Ventricles; Hypertension, Pulmonary; Male; Monocr

2022
PPARĪ³ agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation.
    Science translational medicine, 2018, 04-25, Volume: 10, Issue:438

    Topics: Fatty Acids; Female; Heart Failure; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Oxidation-R

2018
Treatment of PAH with a PPARĪ³ agonist.
    Nature reviews. Cardiology, 2018, Volume: 15, Issue:7

    Topics: Heart Failure; Humans; Hypertension, Pulmonary; Pioglitazone; PPAR gamma

2018
Pioglitazone alleviates cardiac and vascular remodelling and improves survival in monocrotaline induced pulmonary arterial hypertension.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:4

    Topics: Animals; Arterial Pressure; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Heart Ventricle

2016