Page last updated: 2024-11-02

pioglitazone and Pulmonary Arterial Remodeling

pioglitazone has been researched along with Pulmonary Arterial Remodeling in 5 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
"To observe the effect of pioglitazone on carotid artery intima-media thickness (IMT) and plaque-positive rate in patients with metabolic syndrome, and to find a new way to improve arterial remodeling in patients with metabolic syndrome."9.17[Effect of pioglitazone on arteria carotis remodeling in patients with metabolic syndrome]. ( Jiang, D; Jiang, W; Luo, Y; Xu, D, 2013)
"To observe the effect of pioglitazone on carotid artery intima-media thickness (IMT) and plaque-positive rate in patients with metabolic syndrome, and to find a new way to improve arterial remodeling in patients with metabolic syndrome."5.17[Effect of pioglitazone on arteria carotis remodeling in patients with metabolic syndrome]. ( Jiang, D; Jiang, W; Luo, Y; Xu, D, 2013)
"Pulmonary vascular remodeling is an important pathological feature of broiler ascites syndrome."1.91Peroxisome proliferator-activated receptor gamma (PPARγ) activation: a potential treatment for ascites syndrome in broiler chickens. ( Grimes, JL; Karimi Torshizi, MA; Masoudi, AA; Rahimi, M; Rahimi, S; Sharafi, M, 2023)
"Pioglitazone treatment improved survival, reduced PASP, muscularization of small pulmonary arteries, and medial wall thickness."1.43Pioglitazone alleviates cardiac and vascular remodelling and improves survival in monocrotaline induced pulmonary arterial hypertension. ( Baldus, S; Behringer, A; Berghausen, EM; Blaschke, F; Caglayan, E; Er, F; Gassanov, N; Kappert, K; Odenthal, M; Rosenkranz, S; Ten Freyhaus, H; Trappiel, M; Wellnhofer, E, 2016)
"Hyperglycemia was induced by streptozotocin treatment."1.42Hyperglycemia and PPARγ Antagonistically Influence Macrophage Polarization and Infarct Healing After Ischemic Stroke. ( Gliem, M; Hartung, HP; Jander, S; Klotz, L; van Rooijen, N, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Guo, Y1
Zuo, W1
Yin, L1
Gu, T1
Wang, S1
Fang, Z1
Wang, B1
Dong, H1
Hou, W1
Zuo, Z1
Deng, J1
Rahimi, M1
Rahimi, S1
Karimi Torshizi, MA1
Sharafi, M1
Masoudi, AA1
Grimes, JL1
Luo, Y1
Jiang, W1
Xu, D1
Jiang, D1
Gliem, M1
Klotz, L1
van Rooijen, N1
Hartung, HP1
Jander, S1
Behringer, A1
Trappiel, M1
Berghausen, EM1
Ten Freyhaus, H1
Wellnhofer, E1
Odenthal, M1
Blaschke, F1
Er, F1
Gassanov, N1
Rosenkranz, S1
Baldus, S1
Kappert, K1
Caglayan, E1

Trials

1 trial available for pioglitazone and Pulmonary Arterial Remodeling

ArticleYear
[Effect of pioglitazone on arteria carotis remodeling in patients with metabolic syndrome].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2013, Volume: 38, Issue:7

    Topics: Carotid Arteries; Carotid Intima-Media Thickness; Cholesterol, HDL; Drug Therapy, Combination; Femal

2013

Other Studies

4 other studies available for pioglitazone and Pulmonary Arterial Remodeling

ArticleYear
Pioglitazone attenuates ischaemic stroke aggravation by blocking PPARγ reduction and inhibiting chronic inflammation in diabetic mice.
    The European journal of neuroscience, 2022, Volume: 56, Issue:6

    Topics: Animals; Brain Ischemia; Diabetes Mellitus, Experimental; Inflammation; Ischemic Stroke; Mice; NLR F

2022
Peroxisome proliferator-activated receptor gamma (PPARγ) activation: a potential treatment for ascites syndrome in broiler chickens.
    Poultry science, 2023, Volume: 102, Issue:9

    Topics: Animals; Ascites; Chickens; Endothelial Cells; Ligands; Pioglitazone; PPAR gamma; Vascular Remodelin

2023
Hyperglycemia and PPARγ Antagonistically Influence Macrophage Polarization and Infarct Healing After Ischemic Stroke.
    Stroke, 2015, Volume: 46, Issue:10

    Topics: Animals; Anticoagulants; Cell Polarity; Cerebral Hemorrhage; Diabetes Mellitus, Experimental; Diseas

2015
Pioglitazone alleviates cardiac and vascular remodelling and improves survival in monocrotaline induced pulmonary arterial hypertension.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:4

    Topics: Animals; Arterial Pressure; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Heart Ventricle

2016