pioglitazone has been researched along with Pterygium in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Pterygium: An abnormal triangular fold of membrane in the interpalpebral fissure, extending from the conjunctiva to the cornea, being immovably united to the cornea at its apex, firmly attached to the sclera throughout its middle portion, and merged with the conjunctiva at its base. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " This investigation was conducted to determine whether antiproliferative agents such as pioglitazone (PIO) and everolimus (EVE) may inhibit proteins involved in the cholesterol ester cycle and the proliferation of pterygium fibroblasts (PF)." | 3.74 | Modulation of cholesterol homeostasis by antiproliferative drugs in human pterygium fibroblasts. ( Abete, C; Dessì, S; Fossarello, M; Mulas, C; Norfo, C; Peiretti, E; Putzolu, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peiretti, E | 2 |
| Dessì, S | 2 |
| Mulas, MF | 1 |
| Abete, C | 2 |
| Galantuomo, MS | 1 |
| Fossarello, M | 2 |
| Mulas, C | 1 |
| Norfo, C | 1 |
| Putzolu, M | 1 |
2 other studies available for pioglitazone and Pterygium
| Article | Year |
|---|---|
Fibroblasts isolated from human pterygia exhibit altered lipid metabolism characteristics.
Topics: Aged; Case-Control Studies; Cell Proliferation; Cell Separation; Cell Survival; Cells, Cultured; Cho | 2006 |
Modulation of cholesterol homeostasis by antiproliferative drugs in human pterygium fibroblasts.
Topics: Aged; Amides; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caveolin 1; Cell Division; Ce | 2007 |