pioglitazone has been researched along with Polycystic Kidney Diseases in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Polycystic Kidney Diseases: Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Autosomal dominant polycystic kidney disease (ADPKD) is the most common of the monogenic disorders and is characterized by bilateral renal cysts; cysts in other organs including liver, pancreas, spleen, testis and ovary; vascular abnormalities including intracranial aneurysms and subarachnoid hemorrhage; and cardiac disorders such as left ventricular hypertrophy (LVH), mitral valve regurgitation, mitral valve prolapse and aortic regurgitation." | 2.48 | PPAR-γ agonists in polycystic kidney disease with frequent development of cardiovascular disorders. ( Nagao, S; Yamaguchi, T, 2012) |
| "Cystic epithelia in polycystic kidney disease display features similar to malignant cells." | 1.35 | Effect of pioglitazone on survival and renal function in a mouse model of polycystic kidney disease. ( Baird, BC; Germino, GG; Kohan, DE; Piontek, K; Raphael, KL; Strait, KA; Stricklett, PK, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raphael, KL | 1 |
| Strait, KA | 1 |
| Stricklett, PK | 1 |
| Baird, BC | 1 |
| Piontek, K | 1 |
| Germino, GG | 1 |
| Kohan, DE | 1 |
| Nagao, S | 1 |
| Yamaguchi, T | 1 |
1 review available for pioglitazone and Polycystic Kidney Diseases
| Article | Year |
|---|---|
PPAR-γ agonists in polycystic kidney disease with frequent development of cardiovascular disorders.
Topics: Animals; Cardiovascular Diseases; Cell Proliferation; Disease Models, Animal; Fibrosis; Hypoglycemic | 2012 |
1 other study available for pioglitazone and Polycystic Kidney Diseases
| Article | Year |
|---|---|
Effect of pioglitazone on survival and renal function in a mouse model of polycystic kidney disease.
Topics: Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Hypoglycemic Agents; Kaplan-Me | 2009 |