Page last updated: 2024-11-02

pioglitazone and Peripheral Nerve Injuries

pioglitazone has been researched along with Peripheral Nerve Injuries in 5 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Peripheral Nerve Injuries: Injuries to the PERIPHERAL NERVES.

Research Excerpts

ExcerptRelevanceReference
" However, there is no published report on the effect of pioglitazone as an antidepressant in the treatment of depression induced by neuropathic pain with CCI in rats."3.85Possible modulation of PPAR-γ cascade against depression caused by neuropathic pain in rats. ( Deshmukh, VR; Garg, S; Prasoon, P, 2017)
"To examine the effect of pioglitazone on erectile function in a rat model of postprostatectomy erectile dysfunction."3.80Efficacy of pioglitazone on erectile function recovery in a rat model of cavernous nerve injury. ( Aliperti, LA; Gokce, A; Hagan, SS; Hellstrom, JA; Hellstrom, WJ; Kadowitz, PJ; Lasker, GF; Sikka, SC; Trost, LW, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Santos, DFS1
Donahue, RR1
Laird, DE1
Oliveira, MCG1
Taylor, BK1
Garg, S1
Deshmukh, VR1
Prasoon, P1
Heidenberg, DJ1
Haney, NM1
Rezk, BM2
Talwar, S1
Okpechi, SC1
Srivastav, SK1
Honda, M1
Song, B1
Swan, K1
Awadallah, S1
Anaissie, J1
Peak, T2
DeLay, KJ1
Kadowitz, PJ2
Sikka, SC2
Abdel Mageed, AB1
Hellstrom, WJG1
Aliperti, LA1
Lasker, GF2
Hagan, SS1
Hellstrom, JA1
Gokce, A1
Trost, LW1
Hellstrom, WJ2
Katz, EG1
Moustafa, AA1
Heidenberg, D1
Haney, N1
Knoedler, M1
Rittenberg, D1
Abd Elmageed, ZY1
Yafi, FA1
Sikka, S1
Abdel-Mageed, AB1

Other Studies

5 other studies available for pioglitazone and Peripheral Nerve Injuries

ArticleYear
The PPARγ agonist pioglitazone produces a female-predominant inhibition of hyperalgesia associated with surgical incision, peripheral nerve injury, and painful diabetic neuropathy.
    Neuropharmacology, 2022, 03-01, Volume: 205

    Topics: Analgesics; Animals; Diabetic Neuropathies; Disease Models, Animal; Female; Hyperalgesia; Male; Mice

2022
Possible modulation of PPAR-γ cascade against depression caused by neuropathic pain in rats.
    Journal of basic and clinical physiology and pharmacology, 2017, Nov-27, Volume: 28, Issue:6

    Topics: Animals; Brain; Catalase; Depression; Dose-Response Relationship, Drug; Glutathione; Immobility Resp

2017
Pioglitazone's beneficial effects on erectile function preservation after cavernosal nerve injury in the rat are negated by inhibition of the insulin-like growth factor-1 receptor: a preclinical study.
    International journal of impotence research, 2019, Volume: 31, Issue:1

    Topics: Animals; Erectile Dysfunction; Male; Nerve Crush; Nitric Oxide Synthase Type I; Penile Erection; Per

2019
Efficacy of pioglitazone on erectile function recovery in a rat model of cavernous nerve injury.
    Urology, 2014, Volume: 84, Issue:5

    Topics: Animals; Arterial Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Er

2014
Pioglitazone Enhances Survival and Regeneration of Pelvic Ganglion Neurons After Cavernosal Nerve Injury.
    Urology, 2016, Volume: 89

    Topics: Animals; Cell Survival; Male; Nerve Regeneration; Neurons; Pelvis; Peripheral Nerve Injuries; Piogli

2016