pioglitazone has been researched along with Ovarian Neoplasms in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the dose-response analyses, none of the categories showed a significant hazard ratio, and all P-trends were >0." | 1.39 | Pioglitazone does not affect the risk of ovarian cancer: analysis of a nationwide reimbursement database in Taiwan. ( Tseng, CH, 2013) |
| "CGZ and TGZ cause a decrease in ovarian cancer cell proliferation that is PPARγ independent." | 1.37 | Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner. ( Al-Alem, L; Curry, TE; Kilgore, MW; Southard, RC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tseng, CH | 1 |
| Al-Alem, L | 1 |
| Southard, RC | 1 |
| Kilgore, MW | 1 |
| Curry, TE | 1 |
| Shigeto, T | 1 |
| Yokoyama, Y | 1 |
| Xin, B | 1 |
| Mizunuma, H | 1 |
3 other studies available for pioglitazone and Ovarian Neoplasms
| Article | Year |
|---|---|
Pioglitazone does not affect the risk of ovarian cancer: analysis of a nationwide reimbursement database in Taiwan.
Topics: Adult; Aged; Databases, Factual; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Inc | 2013 |
Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromans; Female; Gene Expression; Humans; Ovarian | 2011 |
Peroxisome proliferator-activated receptor alpha and gamma ligands inhibit the growth of human ovarian cancer.
Topics: Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Clofibric Acid; Colony-Forming Units Assay; | 2007 |