pioglitazone has been researched along with Myotonic Dystrophy in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, the effects of pioglitazone in overweight patients with myotonic dystrophy and type 2 diabetes mellitus have not been established." | 7.75 | Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy. ( Abe, H; Funayama, T; Hirose, T; Ikeda, F; Kaga, H; Kanazawa, A; Kawamori, R; Kudo, K; Mita, T; Tokoro, M; Watada, H, 2009) |
| "We report beneficial effects of pioglitazone on insulin resistance in diabetes mellitus accompanied with myotonic dystrophy (DM1)." | 7.73 | [Long-term treatment of diabetes mellitus in myotonic dystrophy with pioglitazone]. ( Isobe, T; Kawai, M; Ogata, K; Ogawa, M; Oya, Y; Shirafuji, T; Yamamoto, T, 2005) |
| "Pioglitazone was effective in improving hyperinsulinemia and reactive hypoglycemia in nondiabetic DM1." | 5.35 | [Successful treatment of recurrent hypoglycemia by pioglitazone in a patient with myotonic dystrophy]. ( Furusawa, Y; Murata, M; Nonaka, I; Oya, Y; Yamamoto, T, 2009) |
| " However, the effects of pioglitazone in overweight patients with myotonic dystrophy and type 2 diabetes mellitus have not been established." | 3.75 | Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy. ( Abe, H; Funayama, T; Hirose, T; Ikeda, F; Kaga, H; Kanazawa, A; Kawamori, R; Kudo, K; Mita, T; Tokoro, M; Watada, H, 2009) |
| "We report beneficial effects of pioglitazone on insulin resistance in diabetes mellitus accompanied with myotonic dystrophy (DM1)." | 3.73 | [Long-term treatment of diabetes mellitus in myotonic dystrophy with pioglitazone]. ( Isobe, T; Kawai, M; Ogata, K; Ogawa, M; Oya, Y; Shirafuji, T; Yamamoto, T, 2005) |
| "Pioglitazone was effective in improving hyperinsulinemia and reactive hypoglycemia in nondiabetic DM1." | 1.35 | [Successful treatment of recurrent hypoglycemia by pioglitazone in a patient with myotonic dystrophy]. ( Furusawa, Y; Murata, M; Nonaka, I; Oya, Y; Yamamoto, T, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, H | 1 |
| Mita, T | 1 |
| Kudo, K | 1 |
| Funayama, T | 1 |
| Tokoro, M | 1 |
| Kaga, H | 1 |
| Ikeda, F | 1 |
| Kanazawa, A | 1 |
| Hirose, T | 1 |
| Kawamori, R | 1 |
| Watada, H | 1 |
| Yamamoto, T | 2 |
| Oya, Y | 2 |
| Furusawa, Y | 1 |
| Nonaka, I | 1 |
| Murata, M | 1 |
| Isobe, T | 1 |
| Shirafuji, T | 1 |
| Ogata, K | 1 |
| Ogawa, M | 1 |
| Kawai, M | 1 |
3 other studies available for pioglitazone and Myotonic Dystrophy
| Article | Year |
|---|---|
Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Myotonic Dystrophy; O | 2009 |
[Successful treatment of recurrent hypoglycemia by pioglitazone in a patient with myotonic dystrophy].
Topics: Adult; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Myotonic Dystrophy; Pioglitazone; Thiazoli | 2009 |
[Long-term treatment of diabetes mellitus in myotonic dystrophy with pioglitazone].
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Mid | 2005 |