pioglitazone has been researched along with Myocarditis in 6 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the long-term effects of the thiazolidinedione PPARgamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats (SHRSP), a model of malignant of hypertension." | 7.72 | Long-term effects of the PPAR gamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats. ( Amiri, F; Benkirane, K; Diep, QN; Paradis, P; Schiffrin, EL, 2004) |
| "We investigated the long-term effects of the thiazolidinedione PPARgamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats (SHRSP), a model of malignant of hypertension." | 3.72 | Long-term effects of the PPAR gamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats. ( Amiri, F; Benkirane, K; Diep, QN; Paradis, P; Schiffrin, EL, 2004) |
| " Then the rats were divided into 3 groups of 9 rats: PPAR-gamma ligand 15-deoxy-(12,14)-PGJ(2) (15d-PGJ(2)) group (15d-PGJ(2) was injected intraperitoneally at the dosage of 200 microg." | 1.32 | [Peroxisome proliferation-activated receptor-gamma ligands ameliorate autoimmune myocarditis associated with inhibition of T cell immunity]. ( Kishimoto, C; Liu, Y; Liu, ZQ; Yuan, ZY; Zhang, JJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, Z | 3 |
| Liu, Y | 8 |
| Zhang, J | 3 |
| Kishimoto, C | 4 |
| Wang, Y | 2 |
| Ma, A | 3 |
| Liu, Z | 3 |
| Yuan, ZY | 1 |
| Zhang, JJ | 1 |
| Liu, ZQ | 1 |
| Diep, QN | 1 |
| Amiri, F | 1 |
| Benkirane, K | 1 |
| Paradis, P | 1 |
| Schiffrin, EL | 1 |
| Hasegawa, H | 1 |
| Takano, H | 1 |
| Zou, Y | 1 |
| Qin, Y | 1 |
| Hizukuri, K | 1 |
| Odaka, K | 1 |
| Toyozaki, T | 1 |
| Komuro, I | 1 |
6 other studies available for pioglitazone and Myocarditis
| Article | Year |
|---|---|
Peroxisome proliferation-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis.
Topics: Animals; Autoimmune Diseases; Hypoglycemic Agents; Interleukin-1; Models, Animal; Myocarditis; Piogl | 2003 |
[Peroxisome proliferation-activated receptor-gamma ligands ameliorate autoimmune myocarditis associated with inhibition of T cell immunity].
Topics: Animals; Autoimmune Diseases; Immunosuppressive Agents; Myocarditis; Pioglitazone; Prostaglandin D2; | 2003 |
Peroxisome proliferator-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis associated with inhibition of self-sensitive T cells.
Topics: Animals; Autoimmune Diseases; Cells, Cultured; Dose-Response Relationship, Drug; Ligands; Myocarditi | 2004 |
Long-term effects of the PPAR gamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Hypertension; Hypertrophy, Left Ventricular; Male; Myocarditis; Pioglitazone; PPAR gamma; R | 2004 |
Pioglitazone, a peroxisome proliferator-activated receptor gamma activator, ameliorates experimental autoimmune myocarditis by modulating Th1/Th2 balance.
Topics: Animals; Autoimmune Diseases; Body Weight; Cytokines; Disease Models, Animal; Female; Hemodynamics; | 2005 |
Cardioprotective effects of peroxisome proliferator activated receptor gamma activators on acute myocarditis: anti-inflammatory actions associated with nuclear factor kappaB blockade.
Topics: Acute Disease; Animals; Autoimmune Diseases; Cardiotonic Agents; Cytokines; Gene Expression Regulati | 2005 |