Page last updated: 2024-11-02

pioglitazone and Kidney, Polycystic

pioglitazone has been researched along with Kidney, Polycystic in 2 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
"Autosomal dominant polycystic kidney disease (ADPKD) is the most common of the monogenic disorders and is characterized by bilateral renal cysts; cysts in other organs including liver, pancreas, spleen, testis and ovary; vascular abnormalities including intracranial aneurysms and subarachnoid hemorrhage; and cardiac disorders such as left ventricular hypertrophy (LVH), mitral valve regurgitation, mitral valve prolapse and aortic regurgitation."2.48PPAR-γ agonists in polycystic kidney disease with frequent development of cardiovascular disorders. ( Nagao, S; Yamaguchi, T, 2012)
"Cystic epithelia in polycystic kidney disease display features similar to malignant cells."1.35Effect of pioglitazone on survival and renal function in a mouse model of polycystic kidney disease. ( Baird, BC; Germino, GG; Kohan, DE; Piontek, K; Raphael, KL; Strait, KA; Stricklett, PK, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raphael, KL1
Strait, KA1
Stricklett, PK1
Baird, BC1
Piontek, K1
Germino, GG1
Kohan, DE1
Nagao, S1
Yamaguchi, T1

Reviews

1 review available for pioglitazone and Kidney, Polycystic

ArticleYear
PPAR-γ agonists in polycystic kidney disease with frequent development of cardiovascular disorders.
    Current molecular pharmacology, 2012, Volume: 5, Issue:2

    Topics: Animals; Cardiovascular Diseases; Cell Proliferation; Disease Models, Animal; Fibrosis; Hypoglycemic

2012

Other Studies

1 other study available for pioglitazone and Kidney, Polycystic

ArticleYear
Effect of pioglitazone on survival and renal function in a mouse model of polycystic kidney disease.
    American journal of nephrology, 2009, Volume: 30, Issue:5

    Topics: Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Hypoglycemic Agents; Kaplan-Me

2009