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pioglitazone and Irritable Bowel Syndrome

pioglitazone has been researched along with Irritable Bowel Syndrome in 2 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.

Research Excerpts

ExcerptRelevanceReference
"Pioglitazone is a peroxisome proliferator-activated receptor (PPAR) γ agonist and, although it is mostly used as an antidiabetic agent, it has been reported to have analgesic effects."5.40Antinociceptive and antidiarrheal effects of pioglitazone in a rat model of diarrhoea-predominant irritable bowel syndrome: role of nitric oxide. ( Azary, S; Dehpour, AR; Gharedaghi, MH; Javidan, AN; Kazemi, MH; Khalifeh-Soltani, A; Moradi, K; Paragomi, P; Rahimian, R; Sakuma, S, 2014)
"Pioglitazone is a peroxisome proliferator-activated receptor (PPAR) γ agonist and, although it is mostly used as an antidiabetic agent, it has been reported to have analgesic effects."1.40Antinociceptive and antidiarrheal effects of pioglitazone in a rat model of diarrhoea-predominant irritable bowel syndrome: role of nitric oxide. ( Azary, S; Dehpour, AR; Gharedaghi, MH; Javidan, AN; Kazemi, MH; Khalifeh-Soltani, A; Moradi, K; Paragomi, P; Rahimian, R; Sakuma, S, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nozu, T1
Miyagishi, S1
Nozu, R1
Takakusaki, K1
Okumura, T1
Paragomi, P1
Rahimian, R1
Kazemi, MH1
Gharedaghi, MH1
Khalifeh-Soltani, A1
Azary, S1
Javidan, AN1
Moradi, K1
Sakuma, S1
Dehpour, AR1

Other Studies

2 other studies available for pioglitazone and Irritable Bowel Syndrome

ArticleYear
Pioglitazone improves visceral sensation and colonic permeability in a rat model of irritable bowel syndrome.
    Journal of pharmacological sciences, 2019, Volume: 139, Issue:1

    Topics: Animals; Colon; Disease Models, Animal; Hyperalgesia; Hypoglycemic Agents; Irritable Bowel Syndrome;

2019
Antinociceptive and antidiarrheal effects of pioglitazone in a rat model of diarrhoea-predominant irritable bowel syndrome: role of nitric oxide.
    Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:2

    Topics: Analgesics; Animals; Antidiarrheals; Diarrhea; Disease Models, Animal; Irritable Bowel Syndrome; Mal

2014