pioglitazone has been researched along with Intracranial Aneurysm in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone treatment reduced the mRNA levels of inflammatory cytokines (monocyte chemoattractant factor-1, interleukin-1, and interleukin-6) that are primarily produced by macrophages in the cerebral arteries." | 1.42 | Protective Role of Peroxisome Proliferator-Activated Receptor-γ in the Development of Intracranial Aneurysm Rupture. ( Furukawa, H; Hashimoto, T; Kitazato, KT; Korai, M; Kuwabara, A; Lawton, MT; Nagahiro, S; Shikata, F; Shimada, K; Tada, Y; Wada, K; Wei, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasan, DM | 1 |
| Starke, RM | 1 |
| Gu, H | 1 |
| Wilson, K | 1 |
| Chu, Y | 1 |
| Chalouhi, N | 1 |
| Heistad, DD | 1 |
| Faraci, FM | 1 |
| Sigmund, CD | 1 |
| Shimada, K | 1 |
| Furukawa, H | 1 |
| Wada, K | 1 |
| Korai, M | 1 |
| Wei, Y | 1 |
| Tada, Y | 1 |
| Kuwabara, A | 1 |
| Shikata, F | 1 |
| Kitazato, KT | 1 |
| Nagahiro, S | 1 |
| Lawton, MT | 1 |
| Hashimoto, T | 1 |
2 other studies available for pioglitazone and Intracranial Aneurysm
| Article | Year |
|---|---|
Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo.
Topics: Aneurysm, Ruptured; Angiotensin II; Anilides; Animals; Cerebral Arteries; Endothelium, Vascular; Gen | 2015 |
Protective Role of Peroxisome Proliferator-Activated Receptor-γ in the Development of Intracranial Aneurysm Rupture.
Topics: Aneurysm, Ruptured; Anilides; Animals; Cerebral Arteries; Cytokines; Hypoglycemic Agents; Intracrani | 2015 |