pioglitazone has been researched along with Hypoxia in 6 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
Excerpt | Relevance | Reference |
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" In the present study, it was examined whether treatment with PPAR‑γ agonist pioglitazone (PIO) is beneficial in counteracting SEV‑induced neuroinflammation and cognitive decline in a rat model of CIH." | 7.91 | Pioglitazone prevents sevoflurane‑induced neuroinflammation and cognitive decline in a rat model of chronic intermittent hypoxia by upregulating hippocampal PPAR‑γ. ( Dong, P; Fei, J; Li, D; Li, L; Li, N; Lin, Q; Lu, L; Yang, B; Zhang, X, 2019) |
" In the present study, it was examined whether treatment with PPAR‑γ agonist pioglitazone (PIO) is beneficial in counteracting SEV‑induced neuroinflammation and cognitive decline in a rat model of CIH." | 3.91 | Pioglitazone prevents sevoflurane‑induced neuroinflammation and cognitive decline in a rat model of chronic intermittent hypoxia by upregulating hippocampal PPAR‑γ. ( Dong, P; Fei, J; Li, D; Li, L; Li, N; Lin, Q; Lu, L; Yang, B; Zhang, X, 2019) |
"Cardiac fibroblasts were exposed to anoxia (95% N2/5% CO2) and then reoxygenation (95% air/5% CO2)." | 1.32 | Anoxia-reoxygenation stimulates collagen type-I and MMP-1 expression in cardiac fibroblasts: modulation by the PPAR-gamma ligand pioglitazone. ( Chen, K; Hermonat, PL; Li, D; Mehta, JL; Zhang, X, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 2 (33.33) | 24.3611 |
2020's | 2 (33.33) | 2.80 |
Authors | Studies |
---|---|
Zhang, H | 2 |
Huang, C | 1 |
Zhang, D | 1 |
Zhu, Y | 1 |
Liu, Y | 1 |
Luo, Q | 1 |
Su, Z | 1 |
Xing, J | 1 |
Wu, J | 1 |
Xiang, L | 1 |
Huang, Y | 1 |
Pan, H | 1 |
Wu, X | 1 |
Zhang, X | 3 |
Li, J | 1 |
Yan, F | 1 |
Li, N | 1 |
Lu, L | 1 |
Lin, Q | 1 |
Li, L | 1 |
Dong, P | 1 |
Yang, B | 1 |
Li, D | 2 |
Fei, J | 1 |
Corsini, I | 1 |
Polvani, S | 1 |
Tarocchi, M | 1 |
Tempesti, S | 1 |
Marroncini, G | 1 |
Generoso, M | 1 |
Bresci, C | 1 |
Gozzini, E | 1 |
Bianconi, T | 1 |
Galli, A | 1 |
Dani, C | 1 |
Chen, K | 1 |
Hermonat, PL | 1 |
Mehta, JL | 1 |
Li, X | 1 |
Kimura, H | 1 |
Hirota, K | 1 |
Sugimoto, H | 1 |
Kimura, N | 1 |
Takahashi, N | 1 |
Fujii, H | 1 |
Yoshida, H | 1 |
6 other studies available for pioglitazone and Hypoxia
Article | Year |
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Pioglitazone Protects Against Hypoxia-Induced Cardiomyocyte Apoptosis Through Inhibiting NLRP3/Caspase-1 Pathway in vivo and in vitro.
Topics: Apoptosis; Caspase 1; Creatine Kinase; Cytochromes c; Eosine Yellowish-(YS); Hematoxylin; Humans; Hy | 2022 |
Suppression of Myocardial Hypoxia-Inducible Factor-1α Compromises Metabolic Adaptation and Impairs Cardiac Function in Patients With Cyanotic Congenital Heart Disease During Puberty.
Topics: Animals; Disease Models, Animal; Fatty Acids; Glucose; Glycolysis; Heart Defects, Congenital; Humans | 2021 |
Pioglitazone prevents sevoflurane‑induced neuroinflammation and cognitive decline in a rat model of chronic intermittent hypoxia by upregulating hippocampal PPAR‑γ.
Topics: Animals; Chronic Disease; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Hypoglycemic A | 2019 |
Peroxisome proliferator-activated receptor-γ agonist pioglitazone reduces the development of necrotizing enterocolitis in a neonatal preterm rat model.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Enterocoliti | 2017 |
Anoxia-reoxygenation stimulates collagen type-I and MMP-1 expression in cardiac fibroblasts: modulation by the PPAR-gamma ligand pioglitazone.
Topics: Animals; Blotting, Western; Collagen Type I; Electrophoretic Mobility Shift Assay; Fibroblasts; Hypo | 2004 |
Hypoxia reduces the expression and anti-inflammatory effects of peroxisome proliferator-activated receptor-gamma in human proximal renal tubular cells.
Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Cyclic N-Oxides; Gene Expression Regulation; Humans; | 2007 |