pioglitazone has been researched along with Hypertension, Renal in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The metabolic syndrome is a risk factor for the development of chronic kidney disease." | 1.35 | Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet. ( Haruna, Y; Kashihara, N; Kobayashi, S; Komai, N; Namikoshi, T; Sasaki, T; Satoh, M; Tomita, N, 2008) |
| "Cystic epithelia in polycystic kidney disease display features similar to malignant cells." | 1.35 | Effect of pioglitazone on survival and renal function in a mouse model of polycystic kidney disease. ( Baird, BC; Germino, GG; Kohan, DE; Piontek, K; Raphael, KL; Strait, KA; Stricklett, PK, 2009) |
| "Our results identify hyperinsulinemia and the attendant increase of TGF-beta expression as potential therapeutic targets in diabetes independent of glycemic control." | 1.34 | Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model. ( Izuhara, Y; Kakuta, T; Miyata, T; Ohtomo, S; Takizawa, S; van Ypersele de Strihou, C; Yamada, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Namikoshi, T | 1 |
| Tomita, N | 1 |
| Satoh, M | 1 |
| Haruna, Y | 1 |
| Kobayashi, S | 1 |
| Komai, N | 1 |
| Sasaki, T | 1 |
| Kashihara, N | 1 |
| Raphael, KL | 1 |
| Strait, KA | 1 |
| Stricklett, PK | 1 |
| Baird, BC | 1 |
| Piontek, K | 1 |
| Germino, GG | 1 |
| Kohan, DE | 1 |
| Ohtomo, S | 1 |
| Izuhara, Y | 1 |
| Takizawa, S | 1 |
| Yamada, N | 1 |
| Kakuta, T | 1 |
| van Ypersele de Strihou, C | 1 |
| Miyata, T | 1 |
3 other studies available for pioglitazone and Hypertension, Renal
| Article | Year |
|---|---|
Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dietary Protei | 2008 |
Effect of pioglitazone on survival and renal function in a mouse model of polycystic kidney disease.
Topics: Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Hypoglycemic Agents; Kaplan-Me | 2009 |
Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glycation End Pr | 2007 |