Page last updated: 2024-11-02

pioglitazone and Headache

pioglitazone has been researched along with Headache in 2 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Research Excerpts

ExcerptRelevanceReference
" The mean half-life was 8 to 9 hours for pioglitazone and 24 to 32 hours for M-III and M-IV, with similar values at each dose level."2.71Single- and multiple-dose pharmacokinetics of pioglitazone in adolescents with type 2 diabetes. ( Burghen, GA; Capparelli, EV; Christensen, ML; Meibohm, B; Tamborlane, WV; Velasquez-Mieyer, P, 2005)
"Two randomized, two-period crossover studies were conducted to evaluate the effects of repeat oral dosing of troglitazone (Study I) and pioglitazone (Study II) on the pharmacokinetics of plasma HMG-CoA reductase inhibitors following multiple oral doses of simvastatin and of simvastatin on the plasma pharmacokinetics of troglitazone (Study I) in healthy subjects."2.70Interactions between simvastatin and troglitazone or pioglitazone in healthy subjects. ( Amin, RD; Dilzer, S; Gagliano, K; Kuznetsova, O; Lasseter, KC; Liu, L; Musser, B; Prueksaritanont, T; Roadcap, BA; Rogers, JD; Vega, JM; Zhao, J, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christensen, ML1
Meibohm, B1
Capparelli, EV1
Velasquez-Mieyer, P1
Burghen, GA1
Tamborlane, WV1
Prueksaritanont, T1
Vega, JM1
Zhao, J1
Gagliano, K1
Kuznetsova, O1
Musser, B1
Amin, RD1
Liu, L1
Roadcap, BA1
Dilzer, S1
Lasseter, KC1
Rogers, JD1

Trials

2 trials available for pioglitazone and Headache

ArticleYear
Single- and multiple-dose pharmacokinetics of pioglitazone in adolescents with type 2 diabetes.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:10

    Topics: Adolescent; Area Under Curve; Cohort Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship,

2005
Interactions between simvastatin and troglitazone or pioglitazone in healthy subjects.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:5

    Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Chromans; Confidence Intervals;

2001