pioglitazone has been researched along with Headache in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mean half-life was 8 to 9 hours for pioglitazone and 24 to 32 hours for M-III and M-IV, with similar values at each dose level." | 2.71 | Single- and multiple-dose pharmacokinetics of pioglitazone in adolescents with type 2 diabetes. ( Burghen, GA; Capparelli, EV; Christensen, ML; Meibohm, B; Tamborlane, WV; Velasquez-Mieyer, P, 2005) |
| "Two randomized, two-period crossover studies were conducted to evaluate the effects of repeat oral dosing of troglitazone (Study I) and pioglitazone (Study II) on the pharmacokinetics of plasma HMG-CoA reductase inhibitors following multiple oral doses of simvastatin and of simvastatin on the plasma pharmacokinetics of troglitazone (Study I) in healthy subjects." | 2.70 | Interactions between simvastatin and troglitazone or pioglitazone in healthy subjects. ( Amin, RD; Dilzer, S; Gagliano, K; Kuznetsova, O; Lasseter, KC; Liu, L; Musser, B; Prueksaritanont, T; Roadcap, BA; Rogers, JD; Vega, JM; Zhao, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christensen, ML | 1 |
| Meibohm, B | 1 |
| Capparelli, EV | 1 |
| Velasquez-Mieyer, P | 1 |
| Burghen, GA | 1 |
| Tamborlane, WV | 1 |
| Prueksaritanont, T | 1 |
| Vega, JM | 1 |
| Zhao, J | 1 |
| Gagliano, K | 1 |
| Kuznetsova, O | 1 |
| Musser, B | 1 |
| Amin, RD | 1 |
| Liu, L | 1 |
| Roadcap, BA | 1 |
| Dilzer, S | 1 |
| Lasseter, KC | 1 |
| Rogers, JD | 1 |
2 trials available for pioglitazone and Headache
| Article | Year |
|---|---|
Single- and multiple-dose pharmacokinetics of pioglitazone in adolescents with type 2 diabetes.
Topics: Adolescent; Area Under Curve; Cohort Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, | 2005 |
Interactions between simvastatin and troglitazone or pioglitazone in healthy subjects.
Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Chromans; Confidence Intervals; | 2001 |