pioglitazone has been researched along with Gallstones in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Gallstones: Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone has a noticeable benefit towards the CGD, which is involved in changes of synthesis, transformation, absorption, and transportation of cholesterol." | 1.51 | Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet. ( Fu, Z; Han, T; Hong, H; Hu, T; Lv, Y; Wang, S, 2019) |
| "The incidences of gallstone formation were 0/8 (group C), 7/8 (group G), and 2/8 (group M) (p < 0." | 1.39 | Retinol-binding protein 4 as a risk factor for cholesterol gallstone formation. ( Fu, Z; Han, T; Sun, Y; Yang, W; Yuan, C; Zhang, D, 2013) |
| "Pioglitazone is a thiazolidinedione that has been shown to improve insulin resistance." | 1.33 | Pioglitazone increases gallbladder volume in insulin-resistant obese mice. ( Al-Azzawi, HH; Lu, D; Mathur, A; Nakeeb, A; Pitt, HA; Swartz-Basile, DA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, T | 2 |
| Lv, Y | 1 |
| Wang, S | 1 |
| Hu, T | 1 |
| Hong, H | 1 |
| Fu, Z | 2 |
| Zhang, D | 1 |
| Sun, Y | 1 |
| Yang, W | 1 |
| Yuan, C | 1 |
| Al-Azzawi, HH | 1 |
| Mathur, A | 1 |
| Lu, D | 1 |
| Swartz-Basile, DA | 1 |
| Nakeeb, A | 1 |
| Pitt, HA | 1 |
3 other studies available for pioglitazone and Gallstones
| Article | Year |
|---|---|
Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet.
Topics: Animals; Anticholesteremic Agents; ATP-Binding Cassette Transporters; Bile Acids and Salts; Choleste | 2019 |
Retinol-binding protein 4 as a risk factor for cholesterol gallstone formation.
Topics: Adult; Aged; Aged, 80 and over; Animals; Case-Control Studies; Cholesterol; Down-Regulation; Female; | 2013 |
Pioglitazone increases gallbladder volume in insulin-resistant obese mice.
Topics: Acetylcholine; Age Factors; Animals; Blood Glucose; Cholecystokinin; Cholinergic Agents; Dietary Car | 2006 |