pioglitazone has been researched along with Fracture, Pathologic in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The use of pioglitazone has been associated with an increased risk of bladder cancer, edema, heart failure, weight gain, and distal bone fractures in postmenopausal women." | 4.89 | [Limitations of insulin-dependent drugs in the treatment of type 2 diabetes mellitus]. ( de Pablos-Velasco, PL; Valerón, PF, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valerón, PF | 1 |
| de Pablos-Velasco, PL | 1 |
| Dormuth, CR | 1 |
| Carney, G | 1 |
| Carleton, B | 1 |
| Bassett, K | 1 |
| Wright, JM | 1 |
| van Troostenburg de Bruyn, AR | 1 |
| Dormandy, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PROspective PioglitAzone Clinical Trial In MacroVascular Events: A Macrovascular Outcome Study in Type 2 Diabetic Patients Comparing Pioglitazone With Placebo in Addition to Existing Therapy[NCT00174993] | Phase 3 | 4,373 participants (Actual) | Interventional | 2001-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pioglitazone and Fracture, Pathologic
| Article | Year |
|---|---|
[Limitations of insulin-dependent drugs in the treatment of type 2 diabetes mellitus].
Topics: Contraindications; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Comb | 2013 |
2 other studies available for pioglitazone and Fracture, Pathologic
| Article | Year |
|---|---|
Thiazolidinediones and fractures in men and women.
Topics: Adult; Aged; British Columbia; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; D | 2009 |
Risk of thiazolidinedione-associated fracture should be appropriately assessed.
Topics: Female; Fractures, Spontaneous; Humans; Hypoglycemic Agents; Pioglitazone; Spinal Fractures; Thiazol | 2010 |