pioglitazone has been researched along with Fibromyalgia in 1 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone significantly relieved fatigue, improved muscle performance, reduced inflammatory cytokines and enhanced antioxidant's activity, while GW9662, a known PPAR-γ antagonist, aggravated the FM manifestations in the rat model." | 8.02 | Pioglitazone improves skeletal muscle functions in reserpine-induced fibromyalgia rat model. ( Attia, MH; Eid, DM; Hassan, FE; Mohamed, AS; Mohie, PM; Sakr, HI; Suliman, HS, 2021) |
| "Pioglitazone significantly relieved fatigue, improved muscle performance, reduced inflammatory cytokines and enhanced antioxidant's activity, while GW9662, a known PPAR-γ antagonist, aggravated the FM manifestations in the rat model." | 4.02 | Pioglitazone improves skeletal muscle functions in reserpine-induced fibromyalgia rat model. ( Attia, MH; Eid, DM; Hassan, FE; Mohamed, AS; Mohie, PM; Sakr, HI; Suliman, HS, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hassan, FE | 1 |
| Sakr, HI | 1 |
| Mohie, PM | 1 |
| Suliman, HS | 1 |
| Mohamed, AS | 1 |
| Attia, MH | 1 |
| Eid, DM | 1 |
1 other study available for pioglitazone and Fibromyalgia
| Article | Year |
|---|---|
Pioglitazone improves skeletal muscle functions in reserpine-induced fibromyalgia rat model.
Topics: Animals; Fatigue; Fibromyalgia; Humans; Male; Muscle, Skeletal; Pioglitazone; PPAR gamma; Rats; Rats | 2021 |