pioglitazone and Fatigue studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

Excerpt	Relevance	Reference
"Pioglitazone significantly relieved fatigue, improved muscle performance, reduced inflammatory cytokines and enhanced antioxidant's activity, while GW9662, a known PPAR-γ antagonist, aggravated the FM manifestations in the rat model."	8.02	Pioglitazone improves skeletal muscle functions in reserpine-induced fibromyalgia rat model. ( Attia, MH; Eid, DM; Hassan, FE; Mohamed, AS; Mohie, PM; Sakr, HI; Suliman, HS, 2021)
"Pioglitazone significantly relieved fatigue, improved muscle performance, reduced inflammatory cytokines and enhanced antioxidant's activity, while GW9662, a known PPAR-γ antagonist, aggravated the FM manifestations in the rat model."	4.02	Pioglitazone improves skeletal muscle functions in reserpine-induced fibromyalgia rat model. ( Attia, MH; Eid, DM; Hassan, FE; Mohamed, AS; Mohie, PM; Sakr, HI; Suliman, HS, 2021)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (100.00)	2.80

pioglitazone and Fatigue

Research Excerpts

Research

Studies (1)

Authors

Other Studies

Authors	Studies
Hassan, FE	1
Sakr, HI	1
Mohie, PM	1
Suliman, HS	1
Mohamed, AS	1
Attia, MH	1
Eid, DM	1