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pioglitazone and Familial Combined Hyperlipidemia

pioglitazone has been researched along with Familial Combined Hyperlipidemia in 3 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
" We hypothesized that pioglitazone treatment of FCH patients might increase insulin sensitivity, but may also improve serum lipid levels, body fat distribution, intramyocellular lipids (IMCL) and endothelial function."5.12Effects of pioglitazone in familial combined hyperlipidaemia. ( Abbink, EJ; De Graaf, J; De Haan, JH; Heerschap, A; Stalenhoef, AF; Tack, CJ, 2006)
"This study's aim was to examine whether treatment with pioglitazone, added to conventional lipid-lowering therapy, would improve myocardial glucose utilization (MGU) and blood flow (MBF) in nondiabetic patients with familial combined hyperlipidemia (FCHL)."5.12Pioglitazone improves myocardial blood flow and glucose utilization in nondiabetic patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled study. ( Betteridge, J; Camici, PG; Holvoet, P; Khan, MT; Kindler, H; Leccisotti, L; Mongillo, M; Naoumova, RP; Neuwirth, C; Seed, M, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brouwers, MC1
de Graaf, J2
van Greevenbroek, MM1
Schaper, N1
Stehouwer, CD1
Stalenhoef, AF2
Abbink, EJ1
De Haan, JH1
Heerschap, A1
Tack, CJ1
Naoumova, RP1
Kindler, H1
Leccisotti, L1
Mongillo, M1
Khan, MT1
Neuwirth, C1
Seed, M1
Holvoet, P1
Betteridge, J1
Camici, PG1

Reviews

1 review available for pioglitazone and Familial Combined Hyperlipidemia

ArticleYear
Novel drugs in familial combined hyperlipidemia: lessons from type 2 diabetes mellitus.
    Current opinion in lipidology, 2010, Volume: 21, Issue:6

    Topics: Adipose Tissue; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Discovery; Fatty Liver; Genetic Pr

2010

Trials

2 trials available for pioglitazone and Familial Combined Hyperlipidemia

ArticleYear
Effects of pioglitazone in familial combined hyperlipidaemia.
    Journal of internal medicine, 2006, Volume: 259, Issue:1

    Topics: Alanine Transaminase; Cholesterol; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperlip

2006
Pioglitazone improves myocardial blood flow and glucose utilization in nondiabetic patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled study.
    Journal of the American College of Cardiology, 2007, Nov-20, Volume: 50, Issue:21

    Topics: Blood Glucose; Coronary Circulation; Double-Blind Method; Drug Therapy, Combination; Female; Glucose

2007