pioglitazone has been researched along with Facial Pain in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Facial Pain: Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 2) Systemic administration of a PPARγ agonist, pioglitazone (PIO), attenuates whisker pad mechanical allodynia at doses of 300 mg/kg i." | 3.85 | PPARγ Agonists Attenuate Trigeminal Neuropathic Pain. ( Danaher, RJ; Lyons, DN; Miller, CS; Westlund, KN; Zhang, L, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lyons, DN | 2 |
| Zhang, L | 2 |
| Danaher, RJ | 2 |
| Miller, CS | 2 |
| Westlund, KN | 2 |
| Pandya, JD | 1 |
| Ma, F | 1 |
| Sullivan, PG | 1 |
| Sirbu, C | 1 |
2 other studies available for pioglitazone and Facial Pain
| Article | Year |
|---|---|
PPARγ Agonists Attenuate Trigeminal Neuropathic Pain.
Topics: Analgesics, Non-Narcotic; Anilides; Animals; Disease Models, Animal; Facial Pain; Hyperalgesia; Male | 2017 |
Combination Drug Therapy of Pioglitazone and D-cycloserine Attenuates Chronic Orofacial Neuropathic Pain and Anxiety by Improving Mitochondrial Function Following Trigeminal Nerve Injury.
Topics: Analgesics; Animals; Anti-Anxiety Agents; Anxiety; Brain; Chronic Pain; Cognition; Cycloserine; Dise | 2018 |