pioglitazone has been researched along with Encephalopathy, Traumatic in 5 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Excerpt | Relevance | Reference |
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" We then hypothesize that optimal pioglitazone dosing will lead to ongoing neuroprotection and cognitive benefits that are dependent on pioglitazone-mitoNEET signalling pathways." | 1.62 | Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury. ( Berkowitz, BA; Burden, S; Cloud, AL; Geldenhuys, WJ; Gooch, JL; Harris, NG; Hubbard, WB; Powell, DK; Spry, ML; Sullivan, PG; Vekaria, HJ, 2021) |
"Pioglitazone treated TBI rats performed significantly better in the RAM test than untreated TBI rats, and similarly to control animals." | 1.51 | Pioglitazone improves working memory performance when administered in chronic TBI. ( Anwar, FN; Correll, EA; Lowery, AC; McCullumsmith, RE; McGuire, JL; Ngwenya, LB; Rhame, K, 2019) |
"Traumatic brain injury is a leading cause of death and disability around the world." | 1.51 | Pioglitazone treatment prior to transplantation improves the efficacy of human mesenchymal stem cells after traumatic brain injury in rats. ( Das, M; Foran, E; Han, JY; Mayilsamy, K; Mohapatra, S; Mohapatra, SS; Tang, X; Willing, AE, 2019) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 3 (60.00) | 2.80 |
Authors | Studies |
---|---|
Hubbard, WB | 2 |
Spry, ML | 1 |
Gooch, JL | 1 |
Cloud, AL | 1 |
Vekaria, HJ | 2 |
Burden, S | 1 |
Powell, DK | 1 |
Berkowitz, BA | 1 |
Geldenhuys, WJ | 2 |
Harris, NG | 1 |
Sullivan, PG | 2 |
Zamanian, MY | 1 |
Taheri, N | 1 |
Opulencia, MJC | 1 |
Bokov, DO | 1 |
Abdullaev, SY | 1 |
Gholamrezapour, M | 1 |
Heidari, M | 1 |
Bazmandegan, G | 1 |
McGuire, JL | 1 |
Correll, EA | 1 |
Lowery, AC | 1 |
Rhame, K | 1 |
Anwar, FN | 1 |
McCullumsmith, RE | 1 |
Ngwenya, LB | 1 |
Das, M | 1 |
Mayilsamy, K | 1 |
Tang, X | 1 |
Han, JY | 1 |
Foran, E | 1 |
Willing, AE | 1 |
Mohapatra, SS | 1 |
Mohapatra, S | 1 |
Yonutas, HM | 1 |
Pandya, JD | 1 |
1 review available for pioglitazone and Encephalopathy, Traumatic
Article | Year |
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Neuroprotective and Anti-inflammatory Effects of Pioglitazone on Traumatic Brain Injury.
Topics: Animals; Anti-Inflammatory Agents; Brain Injuries, Traumatic; Disease Models, Animal; Humans; Microg | 2022 |
4 other studies available for pioglitazone and Encephalopathy, Traumatic
Article | Year |
---|---|
Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; Iron-Binding Proteins; Membrane Proteins; Mice; Mice, Inbred C57 | 2021 |
Pioglitazone improves working memory performance when administered in chronic TBI.
Topics: Animals; Brain; Brain Injuries, Traumatic; Chronic Disease; Male; Maze Learning; Memory, Short-Term; | 2019 |
Pioglitazone treatment prior to transplantation improves the efficacy of human mesenchymal stem cells after traumatic brain injury in rats.
Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Brain Injuries, Traumatic; Brain-Deri | 2019 |
Bioenergetic restoration and neuroprotection after therapeutic targeting of mitoNEET: New mechanism of pioglitazone following traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Energy Metabolism; Iron-Binding Proteins | 2020 |