pioglitazone and Delayed Effects, Prenatal Exposure
pioglitazone has been researched along with Delayed Effects, Prenatal Exposure in 5 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with pioglitazone significantly attenuated the prenatal VPA-induced social impairment, repetitive behavior, hyperactivity, anxiety and low exploratory activity." | 1.51 | Beneficial effects of pioglitazone, a selective peroxisome proliferator-activated receptor-γ agonist in prenatal valproic acid-induced behavioral and biochemical autistic like features in Wistar rats. ( Mirza, R; Sharma, B, 2019) |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Liu, WC | 2 |
| Wu, CW | 2 |
| Fu, MH | 2 |
| Tain, YL | 2 |
| Liang, CK | 2 |
| Hung, CY | 2 |
| Chen, IC | 1 |
| Lee, YC | 1 |
| Wu, CY | 1 |
| Wu, KLH | 2 |
| Sağır, D | 1 |
| Zhao, Q | 1 |
| Wang, Q | 1 |
| Wang, J | 1 |
| Tang, M | 1 |
| Huang, S | 1 |
| Peng, K | 1 |
| Han, Y | 1 |
| Zhang, J | 1 |
| Liu, G | 1 |
| Fang, Q | 1 |
| You, Z | 1 |
| Hirase, H | 1 |
| Lee, WC | 1 |
| Chan, JYH | 1 |
| Chen, LW | 1 |
| Ho, YH | 1 |
| Kung, YC | 1 |
| Leu, S | 1 |
| Mirza, R | 1 |
| Sharma, B | 1 |
Other Studies
5 other studies available for pioglitazone and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Maternal high fructose-induced hippocampal neuroinflammation in the adult female offspring via PPARγ-NF-κB signaling.
Topics: Animals; Cytokines; Diet; Female; Fructose; Hippocampus; Inflammation; Inflammation Mediators; Male; | 2020 |
Dose-dependent effects of prenatal exposure of pioglitazone, the PPARγ agonist, on the hippocampus development and learning and memory performance of rat offspring.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Gestational Age; Glial Fibrilla | 2021 |
Maternal immune activation-induced PPARγ-dependent dysfunction of microglia associated with neurogenic impairment and aberrant postnatal behaviors in offspring.
Topics: Animals; Behavior, Animal; Female; Hippocampus; Microglia; Neurogenesis; Pioglitazone; PPAR gamma; P | 2019 |
Pioglitazone reversed the fructose-programmed astrocytic glycolysis and oxidative phosphorylation of female rat offspring.
Topics: Animals; Astrocytes; Dietary Sugars; DNA, Mitochondrial; Female; Fetal Development; Fructose; Glucos | 2019 |
Beneficial effects of pioglitazone, a selective peroxisome proliferator-activated receptor-γ agonist in prenatal valproic acid-induced behavioral and biochemical autistic like features in Wistar rats.
Topics: Animals; Anticonvulsants; Anxiety; Autism Spectrum Disorder; Brain Chemistry; Cytokines; Exploratory | 2019 |