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pioglitazone and Delayed Effects, Prenatal Exposure

pioglitazone has been researched along with Delayed Effects, Prenatal Exposure in 5 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
"Treatment with pioglitazone significantly attenuated the prenatal VPA-induced social impairment, repetitive behavior, hyperactivity, anxiety and low exploratory activity."1.51Beneficial effects of pioglitazone, a selective peroxisome proliferator-activated receptor-γ agonist in prenatal valproic acid-induced behavioral and biochemical autistic like features in Wistar rats. ( Mirza, R; Sharma, B, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Liu, WC2
Wu, CW2
Fu, MH2
Tain, YL2
Liang, CK2
Hung, CY2
Chen, IC1
Lee, YC1
Wu, CY1
Wu, KLH2
Sağır, D1
Zhao, Q1
Wang, Q1
Wang, J1
Tang, M1
Huang, S1
Peng, K1
Han, Y1
Zhang, J1
Liu, G1
Fang, Q1
You, Z1
Hirase, H1
Lee, WC1
Chan, JYH1
Chen, LW1
Ho, YH1
Kung, YC1
Leu, S1
Mirza, R1
Sharma, B1

Other Studies

5 other studies available for pioglitazone and Delayed Effects, Prenatal Exposure

ArticleYear
Maternal high fructose-induced hippocampal neuroinflammation in the adult female offspring via PPARγ-NF-κB signaling.
    The Journal of nutritional biochemistry, 2020, Volume: 81

    Topics: Animals; Cytokines; Diet; Female; Fructose; Hippocampus; Inflammation; Inflammation Mediators; Male;

2020
Dose-dependent effects of prenatal exposure of pioglitazone, the PPARγ agonist, on the hippocampus development and learning and memory performance of rat offspring.
    Toxicology and applied pharmacology, 2021, 06-15, Volume: 421

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Gestational Age; Glial Fibrilla

2021
Maternal immune activation-induced PPARγ-dependent dysfunction of microglia associated with neurogenic impairment and aberrant postnatal behaviors in offspring.
    Neurobiology of disease, 2019, Volume: 125

    Topics: Animals; Behavior, Animal; Female; Hippocampus; Microglia; Neurogenesis; Pioglitazone; PPAR gamma; P

2019
Pioglitazone reversed the fructose-programmed astrocytic glycolysis and oxidative phosphorylation of female rat offspring.
    American journal of physiology. Endocrinology and metabolism, 2019, 04-01, Volume: 316, Issue:4

    Topics: Animals; Astrocytes; Dietary Sugars; DNA, Mitochondrial; Female; Fetal Development; Fructose; Glucos

2019
Beneficial effects of pioglitazone, a selective peroxisome proliferator-activated receptor-γ agonist in prenatal valproic acid-induced behavioral and biochemical autistic like features in Wistar rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2019, Volume: 76

    Topics: Animals; Anticonvulsants; Anxiety; Autism Spectrum Disorder; Brain Chemistry; Cytokines; Exploratory

2019
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