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pioglitazone and Degenerative Diseases, Central Nervous System

pioglitazone has been researched along with Degenerative Diseases, Central Nervous System in 4 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
" Herein, we have studied the potential of nanomedicine to prepare a single platform based on mesoporous silica nanoparticles (MSNs) for the treatment of an ALS animal model with a cocktail of agents such as leptin (neuroprotective) and pioglitazone (anti-inflammatory), which have already demonstrated promising therapeutic ability in other neurodegenerative diseases."8.12Design of Mesoporous Silica Nanoparticles for the Treatment of Amyotrophic Lateral Sclerosis (ALS) with a Therapeutic Cocktail Based on Leptin and Pioglitazone. ( Cabrera-Pinto, M; Díaz-García, D; Díaz-Sánchez, M; Fernandez-Martos, CM; Ferrer-Donato, Á; Gómez-Ruiz, S; Méndez-Arriaga, JM; Prashar, S, 2022)
" Herein, we have studied the potential of nanomedicine to prepare a single platform based on mesoporous silica nanoparticles (MSNs) for the treatment of an ALS animal model with a cocktail of agents such as leptin (neuroprotective) and pioglitazone (anti-inflammatory), which have already demonstrated promising therapeutic ability in other neurodegenerative diseases."4.12Design of Mesoporous Silica Nanoparticles for the Treatment of Amyotrophic Lateral Sclerosis (ALS) with a Therapeutic Cocktail Based on Leptin and Pioglitazone. ( Cabrera-Pinto, M; Díaz-García, D; Díaz-Sánchez, M; Fernandez-Martos, CM; Ferrer-Donato, Á; Gómez-Ruiz, S; Méndez-Arriaga, JM; Prashar, S, 2022)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Blackburn, JK1
Jamwal, S1
Wang, W1
Elsworth, JD1
Díaz-García, D1
Ferrer-Donato, Á1
Méndez-Arriaga, JM1
Cabrera-Pinto, M1
Díaz-Sánchez, M1
Prashar, S1
Fernandez-Martos, CM1
Gómez-Ruiz, S1
Basagni, F1
Di Paolo, ML1
Cozza, G1
Dalla Via, L1
Fagiani, F1
Lanni, C1
Rosini, M1
Minarini, A1
Thal, SC1
Neuhaus, W1

Reviews

1 review available for pioglitazone and Degenerative Diseases, Central Nervous System

ArticleYear
The blood-brain barrier as a target in traumatic brain injury treatment.
    Archives of medical research, 2014, Volume: 45, Issue:8

    Topics: Blood-Brain Barrier; Brain Edema; Brain Injuries; Cell Hypoxia; Humans; Hypoglycemic Agents; Inflamm

2014

Other Studies

3 other studies available for pioglitazone and Degenerative Diseases, Central Nervous System

ArticleYear
Pioglitazone transiently stimulates paraoxonase-2 expression in male nonhuman primate brain: Implications for sex-specific therapeutics in neurodegenerative disorders.
    Neurochemistry international, 2022, Volume: 152

    Topics: Animals; Aryldialkylphosphatase; Brain; Female; Mitochondria; Neurodegenerative Diseases; Neuroprote

2022
Design of Mesoporous Silica Nanoparticles for the Treatment of Amyotrophic Lateral Sclerosis (ALS) with a Therapeutic Cocktail Based on Leptin and Pioglitazone.
    ACS biomaterials science & engineering, 2022, Nov-14, Volume: 8, Issue:11

    Topics: Amyotrophic Lateral Sclerosis; Animals; DNA-Binding Proteins; Leptin; Mice; Mice, Transgenic; Nanopa

2022
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets.
    Molecules (Basel, Switzerland), 2023, Nov-04, Volume: 28, Issue:21

    Topics: Antioxidants; Humans; Monoamine Oxidase; Neurodegenerative Diseases; NF-E2-Related Factor 2; Oxidati

2023