pioglitazone has been researched along with Death, Sudden, Cardiac in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
| Excerpt | Relevance | Reference |
|---|---|---|
| "pioglitazone) users was 0." | 5.56 | The risk of sudden cardiac arrest and ventricular arrhythmia with rosiglitazone versus pioglitazone: real-world evidence on thiazolidinedione safety. ( Aquilante, CL; Bilker, WB; Bloomgarden, ZT; Brensinger, CM; Dawwas, GK; Deo, R; Dhopeshwarkar, N; Flory, JH; Gagne, JJ; Hennessy, S; Kimmel, SE; Leonard, CE; Soprano, SE, 2020) |
| " In this study, we investigated whether TZDs affect onset, spectral characteristics, and mortality of ischemic ventricular fibrillation (VF) and whether such effects are recapitulated by a non-selective K(ATP) blocker (glyburide) or a mitochondrial K(ATP) blocker (5-hydroxydecanoate)." | 3.78 | Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs. ( Greyson, CR; Lu, L; Reiter, MJ; Sarraf, M; Schwartz, GG; Ye, S, 2012) |
| "pioglitazone) users was 0." | 1.56 | The risk of sudden cardiac arrest and ventricular arrhythmia with rosiglitazone versus pioglitazone: real-world evidence on thiazolidinedione safety. ( Aquilante, CL; Bilker, WB; Bloomgarden, ZT; Brensinger, CM; Dawwas, GK; Deo, R; Dhopeshwarkar, N; Flory, JH; Gagne, JJ; Hennessy, S; Kimmel, SE; Leonard, CE; Soprano, SE, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Leonard, CE | 1 |
| Brensinger, CM | 1 |
| Dawwas, GK | 1 |
| Deo, R | 1 |
| Bilker, WB | 1 |
| Soprano, SE | 1 |
| Dhopeshwarkar, N | 1 |
| Flory, JH | 1 |
| Bloomgarden, ZT | 1 |
| Gagne, JJ | 1 |
| Aquilante, CL | 1 |
| Kimmel, SE | 1 |
| Hennessy, S | 1 |
| Morrow, JP | 1 |
| Katchman, A | 1 |
| Son, NH | 1 |
| Trent, CM | 1 |
| Khan, R | 1 |
| Shiomi, T | 1 |
| Huang, H | 1 |
| Amin, V | 1 |
| Lader, JM | 1 |
| Vasquez, C | 1 |
| Morley, GE | 1 |
| D'Armiento, J | 1 |
| Homma, S | 1 |
| Goldberg, IJ | 1 |
| Marx, SO | 1 |
| Sarraf, M | 1 |
| Lu, L | 1 |
| Ye, S | 1 |
| Reiter, MJ | 1 |
| Greyson, CR | 1 |
| Schwartz, GG | 1 |
3 other studies available for pioglitazone and Death, Sudden, Cardiac
| Article | Year |
|---|---|
The risk of sudden cardiac arrest and ventricular arrhythmia with rosiglitazone versus pioglitazone: real-world evidence on thiazolidinedione safety.
Topics: Adult; Aged; Arrhythmias, Cardiac; Databases, Factual; Death, Sudden, Cardiac; Diabetes Mellitus, Ty | 2020 |
Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias.
Topics: Action Potentials; Animals; Calcium; Connexin 43; Death, Sudden, Cardiac; Disease Models, Animal; El | 2011 |
Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Vessels; Death, Sudden, Cardiac; Decanoic Acids; Female; G | 2012 |