Page last updated: 2024-11-02

pioglitazone and Chromosomal Translocation

pioglitazone has been researched along with Chromosomal Translocation in 2 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
"Approximately 35% of follicular thyroid carcinomas harbor a chromosomal translocation that results in expression of a paired box gene 8-peroxisome proliferator-activated receptor γ gene (PPARγ) fusion protein (PPFP)."1.37Pioglitazone induces a proadipogenic antitumor response in mice with PAX8-PPARgamma fusion protein thyroid carcinoma. ( Colby, LA; Diallo-Krou, E; Dobson, ME; Giordano, TJ; Grachtchouk, V; Koenig, RJ; Wilkinson, JE; Yu, J, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, Y1
Yu, J2
Grachtchouk, V2
Qin, T1
Lumeng, CN1
Sartor, MA1
Koenig, RJ2
Dobson, ME1
Diallo-Krou, E1
Colby, LA1
Wilkinson, JE1
Giordano, TJ1

Other Studies

2 other studies available for pioglitazone and Chromosomal Translocation

ArticleYear
Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer.
    Oncotarget, 2017, Jan-24, Volume: 8, Issue:4

    Topics: Adenocarcinoma, Follicular; Animals; Binding Sites; Chromatin Immunoprecipitation; Disease Models, A

2017
Pioglitazone induces a proadipogenic antitumor response in mice with PAX8-PPARgamma fusion protein thyroid carcinoma.
    Endocrinology, 2011, Volume: 152, Issue:11

    Topics: Adenocarcinoma, Follicular; Adipogenesis; Animals; Mice; Mice, Transgenic; Oncogene Proteins, Fusion

2011