pioglitazone has been researched along with Cell Transformation, Neoplastic in 4 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone was introduced by oral gavage." | 1.37 | Chemoprevention of lung carcinogenesis by the combination of aerosolized budesonide and oral pioglitazone in A/J mice. ( Chen, DR; Chen, R; Fu, H; Lu, Y; Lubet, RA; Pan, J; Szabo, E; Wang, Y; Wen, W; You, M; Zhang, J; Zhang, Q, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atlı Şekeroğlu, Z | 1 |
| Şekeroğlu, V | 1 |
| Kontaş Yedier, S | 1 |
| İlkun, E | 1 |
| Liou, LS | 1 |
| Fu, H | 1 |
| Zhang, J | 1 |
| Pan, J | 1 |
| Zhang, Q | 1 |
| Lu, Y | 1 |
| Wen, W | 1 |
| Lubet, RA | 1 |
| Szabo, E | 1 |
| Chen, R | 1 |
| Wang, Y | 1 |
| Chen, DR | 1 |
| You, M | 1 |
| Li, MY | 1 |
| Kong, AW | 1 |
| Yuan, H | 1 |
| Ma, LT | 1 |
| Hsin, MK | 1 |
| Wan, IY | 1 |
| Underwood, MJ | 1 |
| Chen, GG | 1 |
| Fujisawa, T | 1 |
| Nakajima, A | 1 |
| Fujisawa, N | 1 |
| Takahashi, H | 1 |
| Ikeda, I | 1 |
| Tomimoto, A | 1 |
| Yonemitsu, K | 1 |
| Nakajima, N | 1 |
| Kudo, C | 1 |
| Wada, K | 1 |
| Kubota, N | 1 |
| Terauchi, Y | 1 |
| Kadowaki, T | 1 |
| Nakagama, H | 1 |
| Blumberg, RS | 1 |
4 other studies available for pioglitazone and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Increased DNA strand breaks and neoplastic transformation in human bladder cells treated with pioglitazone.
Topics: Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Diabetes Mellitus, Type 2; DNA; DN | 2021 |
Chemoprevention of lung carcinogenesis by the combination of aerosolized budesonide and oral pioglitazone in A/J mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Budesonide; Carcinogens; Ce | 2011 |
Pioglitazone prevents smoking carcinogen-induced lung tumor development in mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transformati | 2012 |
Peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses colonic epithelial cell turnover and colon carcinogenesis through inhibition of the beta-catenin/T cell factor (TCF) pathway.
Topics: Active Transport, Cell Nucleus; Animals; Azoxymethane; beta Catenin; Caco-2 Cells; Cell Proliferatio | 2008 |