Page last updated: 2024-11-02

pioglitazone and Carotid Stenosis

pioglitazone has been researched along with Carotid Stenosis in 2 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)

Research Excerpts

ExcerptRelevanceReference
"This study examined whether pioglitazone, an agonist of peroxisome proliferator-activated receptor gamma, may stabilize vulnerable plaque with use of ultrasound evaluation of carotid artery plaque echolucency in patients with acute coronary syndrome (ACS) and type 2 diabetes mellitus (DM)."9.14Rapid improvement of carotid plaque echogenicity within 1 month of pioglitazone treatment in patients with acute coronary syndrome. ( Fujioka, D; Hirano, M; Kawabata, K; Kitta, Y; Kobayashi, T; Kodama, Y; Kugiyama, K; Nakamura, K; Nakamura, T; Obata, JE; Saito, Y; Sano, K; Yano, T, 2009)
"This study examined whether pioglitazone, an agonist of peroxisome proliferator-activated receptor gamma, may stabilize vulnerable plaque with use of ultrasound evaluation of carotid artery plaque echolucency in patients with acute coronary syndrome (ACS) and type 2 diabetes mellitus (DM)."5.14Rapid improvement of carotid plaque echogenicity within 1 month of pioglitazone treatment in patients with acute coronary syndrome. ( Fujioka, D; Hirano, M; Kawabata, K; Kitta, Y; Kobayashi, T; Kodama, Y; Kugiyama, K; Nakamura, K; Nakamura, T; Obata, JE; Saito, Y; Sano, K; Yano, T, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirano, M1
Nakamura, T1
Kitta, Y1
Yano, T1
Kobayashi, T1
Sano, K1
Fujioka, D1
Saito, Y1
Kodama, Y1
Kawabata, K1
Nakamura, K1
Obata, JE1
Kugiyama, K1

Trials

1 trial available for pioglitazone and Carotid Stenosis

ArticleYear
Rapid improvement of carotid plaque echogenicity within 1 month of pioglitazone treatment in patients with acute coronary syndrome.
    Atherosclerosis, 2009, Volume: 203, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Calibration; Carotid Stenosis; Diabetes Complications; Diabetes Melli

2009

Other Studies

1 other study available for pioglitazone and Carotid Stenosis

ArticleYear
[Early effect of therapy with pioglitazone. Vascular damage significantly reduced].
    MMW Fortschritte der Medizin, 2002, May-23, Volume: 144, Issue:21

    Topics: Arteriosclerosis; Carotid Stenosis; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic An

2002