Page last updated: 2024-11-02

pioglitazone and Cancer of Kidney

pioglitazone has been researched along with Cancer of Kidney in 6 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
"We enrolled 45 patients with metastatic renal cell carcinoma (RCC) at a progressive disease between March 2003 and April 2008 to assess the impact of an anti-inflammatory treatment regime in combination with metronomic low-dose chemotherapy."2.77Pioglitazone, etoricoxib, interferon-α, and metronomic capecitabine for metastatic renal cell carcinoma: final results of a prospective phase II trial. ( Andreesen, R; Berand, A; Bross, K; Grassinger, J; Reichle, A; Rogenhofer, S; Schrettenbrunner, I; Suedhoff, T; Vogelhuber, M; Walter, B; Wieland, WF; Wilke, J, 2012)
" None of the dose-response parameters showed a significant trend of risk association, with all P-trends >0."1.40Pioglitazone does not affect the risk of kidney cancer in patients with type 2 diabetes. ( Tseng, CH, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tseng, CH1
Walter, B1
Schrettenbrunner, I1
Vogelhuber, M1
Grassinger, J1
Bross, K1
Wilke, J1
Suedhoff, T1
Berand, A1
Wieland, WF1
Rogenhofer, S1
Andreesen, R1
Reichle, A1
Mahmoud, MF1
El Shazly, SM1
Yuan, J1
Takahashi, A1
Masumori, N1
Uchida, K1
Hisasue, S1
Kitamura, H1
Itoh, N1
Tsukamoto, T1
Yang, FG1
Zhang, ZW1
Xin, DQ1
Shi, CJ1
Wu, JP1
Guo, YL1
Guan, YF1
Inoue, K1
Kawahito, Y1
Tsubouchi, Y1
Kohno, M1
Yoshimura, R1
Yoshikawa, T1
Sano, H1

Trials

1 trial available for pioglitazone and Cancer of Kidney

ArticleYear
Pioglitazone, etoricoxib, interferon-α, and metronomic capecitabine for metastatic renal cell carcinoma: final results of a prospective phase II trial.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antiviral Age

2012

Other Studies

5 other studies available for pioglitazone and Cancer of Kidney

ArticleYear
Pioglitazone does not affect the risk of kidney cancer in patients with type 2 diabetes.
    Metabolism: clinical and experimental, 2014, Volume: 63, Issue:8

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Kidney Neoplasms; Male;

2014
Pioglitazone protects against cisplatin induced nephrotoxicity in rats and potentiates its anticancer activity against human renal adenocarcinoma cell lines.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 51

    Topics: Animals; Benzhydryl Compounds; Carcinoma, Renal Cell; Cell Line, Tumor; Cisplatin; Epoxy Compounds;

2013
Ligands for peroxisome proliferator-activated receptor gamma have potent antitumor effect against human renal cell carcinoma.
    Urology, 2005, Volume: 65, Issue:3

    Topics: Carcinoma, Renal Cell; Cell Division; Dose-Response Relationship, Drug; Humans; Kidney Neoplasms; Pi

2005
Peroxisome proliferator-activated receptor gamma ligands induce cell cycle arrest and apoptosis in human renal carcinoma cell lines.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Chrom

2005
Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists.
    Biochemical and biophysical research communications, 2001, Sep-28, Volume: 287, Issue:3

    Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Renal Cell; Cell Division; Chromans; Coloring A

2001