pioglitazone has been researched along with Cachexia in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Cachexia: General ill health, malnutrition, and weight loss, usually associated with chronic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combined treatment with INS 18 U/kg + PIO 5 mg/kg was more effective in preventing advanced cachexia in TB rats than each treatment alone, emerging as the best approach, considering the lower dosage and higher efficacy." | 5.91 | Insulin in combination with pioglitazone prevents advanced cachexia in 256-Walker tumor-bearing rats: effect is greater than treatment alone and is associated with improved insulin sensitivity. ( Bazotte, RB; Bertolini, GL; Biazi, GR; Cassolla, P; de Souza Galia, WB; de Souza, HM; Diaz, BF; Ferraz, LS; Frasson, IG; Kurauti, MA; Mareze-Costa, CE; Marmentini, C; Miksza, DR; Peres, SB, 2023) |
| "Cachexia is a multifactorial syndrome characterized by profound involuntary weight loss, fat depletion, skeletal muscle wasting, and asthenia; all symptoms are not entirely attributable to inadequate nutritional intake." | 5.42 | Pioglitazone treatment increases survival and prevents body weight loss in tumor-bearing animals: possible anti-cachectic effect. ( Andreotti, S; Batista, ML; Beluzi, M; Farmer, SR; Franco, FO; Henriques, FS; Knobl, P; Lima, FB; Neves, RX; Peres, SB; Santos, KB; Seelaender, M; Sertié, RA; Shida, CS, 2015) |
| "The combined treatment with INS 18 U/kg + PIO 5 mg/kg was more effective in preventing advanced cachexia in TB rats than each treatment alone, emerging as the best approach, considering the lower dosage and higher efficacy." | 1.91 | Insulin in combination with pioglitazone prevents advanced cachexia in 256-Walker tumor-bearing rats: effect is greater than treatment alone and is associated with improved insulin sensitivity. ( Bazotte, RB; Bertolini, GL; Biazi, GR; Cassolla, P; de Souza Galia, WB; de Souza, HM; Diaz, BF; Ferraz, LS; Frasson, IG; Kurauti, MA; Mareze-Costa, CE; Marmentini, C; Miksza, DR; Peres, SB, 2023) |
| "Cachexia is a multifactorial syndrome characterized by profound involuntary weight loss, fat depletion, skeletal muscle wasting, and asthenia; all symptoms are not entirely attributable to inadequate nutritional intake." | 1.42 | Pioglitazone treatment increases survival and prevents body weight loss in tumor-bearing animals: possible anti-cachectic effect. ( Andreotti, S; Batista, ML; Beluzi, M; Farmer, SR; Franco, FO; Henriques, FS; Knobl, P; Lima, FB; Neves, RX; Peres, SB; Santos, KB; Seelaender, M; Sertié, RA; Shida, CS, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Miksza, DR | 1 |
| Biazi, GR | 1 |
| Frasson, IG | 1 |
| de Souza Galia, WB | 2 |
| Ferraz, LS | 1 |
| Diaz, BF | 1 |
| Kurauti, MA | 1 |
| Marmentini, C | 1 |
| Mareze-Costa, CE | 1 |
| Peres, SB | 2 |
| Cassolla, P | 2 |
| Bertolini, GL | 1 |
| Bazotte, RB | 1 |
| de Souza, HM | 2 |
| Beluzi, M | 1 |
| Henriques, FS | 1 |
| Sertié, RA | 1 |
| Franco, FO | 1 |
| Santos, KB | 1 |
| Knobl, P | 1 |
| Andreotti, S | 1 |
| Shida, CS | 1 |
| Neves, RX | 1 |
| Farmer, SR | 1 |
| Seelaender, M | 1 |
| Lima, FB | 1 |
| Batista, ML | 1 |
| de Fatima Silva, F | 1 |
| Ortiz-Silva, M | 1 |
| Graciano, MF | 1 |
| Zaia, CT | 1 |
| Zaia, D | 1 |
| Carpinelli, ÂR | 1 |
| da Silva, FG | 1 |
3 other studies available for pioglitazone and Cachexia
| Article | Year |
|---|---|
Insulin in combination with pioglitazone prevents advanced cachexia in 256-Walker tumor-bearing rats: effect is greater than treatment alone and is associated with improved insulin sensitivity.
Topics: Animals; Cachexia; Hypoglycemic Agents; Insulin; Insulin Resistance; Neoplasms; Pioglitazone; Rats; | 2023 |
Pioglitazone treatment increases survival and prevents body weight loss in tumor-bearing animals: possible anti-cachectic effect.
Topics: Adiponectin; Adipose Tissue; Animals; Body Weight; Cachexia; Carcinoma 256, Walker; CCAAT-Enhancer-B | 2015 |
Pioglitazone improves insulin sensitivity and reduces weight loss in Walker-256 tumor-bearing rats.
Topics: Animals; Cachexia; Insulin Resistance; Male; Pioglitazone; Rats; Rats, Wistar; Thiazolidinediones; W | 2017 |