Page last updated: 2024-11-02

pioglitazone and Bile Duct Obstruction

pioglitazone has been researched along with Bile Duct Obstruction in 3 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with pioglitazone dose-dependently attenuated gastric lesions induced by ethanol in both sham and cholestatic rats, but this effect was more prominent in cholestatic ones."1.40The increased gastroprotective effect of pioglitazone in cholestatic rats: role of nitric oxide and tumour necrosis factor alpha. ( Amirghofran, Z; Dehpour, AR; Janahmadi, Z; Moezi, L; Nekooeian, AA, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dawson, S1
Stahl, S1
Paul, N1
Barber, J1
Kenna, JG1
Moezi, L1
Janahmadi, Z1
Amirghofran, Z1
Nekooeian, AA1
Dehpour, AR1
Pinto, AG1
Cummings, OW1
Chalasani, N1

Other Studies

3 other studies available for pioglitazone and Bile Duct Obstruction

ArticleYear
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
The increased gastroprotective effect of pioglitazone in cholestatic rats: role of nitric oxide and tumour necrosis factor alpha.
    International journal of experimental pathology, 2014, Volume: 95, Issue:1

    Topics: Animals; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Interleukin

2014
Severe but reversible cholestatic liver injury after pioglitazone therapy.
    Annals of internal medicine, 2002, Nov-19, Volume: 137, Issue:10

    Topics: Cholestasis; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Middle Aged; Pioglitazo

2002