pioglitazone has been researched along with Berardinelli Syndrome in 5 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone treatment increased energy expenditure and improved insulin resistance, hypotriglyceridaemia and liver steatosis in these mice." | 1.39 | Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice. ( Capeau, J; Cariou, B; Costet, P; Dollet, L; Fève, B; Lathrop, M; Le May, C; Magré, J; Matsuda, F; Mounier, C; Nemani, M; Pillot, B; Prieur, X; Takahashi, M; Takigawa-Imamura, H; Zelenika, D, 2013) |
| "Berardinelli- Seip syndrome is an autosomal recessive disorder characterized by generalized lipoatrophy, extreme insulin resistance with dyslipidemia in childhood and development of diabetes in adolescence." | 1.38 | An unusual cause of delayed puberty: Berardinelli- Seip syndrome. ( Dhull, P; Kumar, KV; Patnaik, SK; Upreti, V, 2012) |
| "Beradinelli-Seip congenital generalized lipodystrophy is a rare autosomal recessive disorder characterized by near-complete absence of adipose tissue, Herculean appearance, insulin resistance, hypoleptinaemia and diabetes mellitus." | 1.36 | Reduced adipogenic gene expression in fibroblasts from a patient with type 2 congenital generalized lipodystrophy. ( Araújo-Vilar, D; Barreiro, F; Cabezas-Agrícola, JM; Calvo, C; Del Coco, R; González-Méndez, B; Lado-Abeal, J; Lattanzi, G; Loidi, L; Victoria, B, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, R | 1 |
| Pilania, RK | 1 |
| Bhatia, A | 1 |
| Dayal, D | 1 |
| Upreti, V | 1 |
| Dhull, P | 1 |
| Patnaik, SK | 1 |
| Kumar, KV | 1 |
| Prieur, X | 1 |
| Dollet, L | 1 |
| Takahashi, M | 1 |
| Nemani, M | 1 |
| Pillot, B | 1 |
| Le May, C | 1 |
| Mounier, C | 1 |
| Takigawa-Imamura, H | 1 |
| Zelenika, D | 1 |
| Matsuda, F | 1 |
| Fève, B | 1 |
| Capeau, J | 1 |
| Lathrop, M | 1 |
| Costet, P | 1 |
| Cariou, B | 1 |
| Magré, J | 1 |
| Chen, W | 1 |
| Yechoor, VK | 1 |
| Chang, BH | 1 |
| Li, MV | 1 |
| March, KL | 1 |
| Chan, L | 1 |
| Victoria, B | 1 |
| Cabezas-Agrícola, JM | 1 |
| González-Méndez, B | 1 |
| Lattanzi, G | 1 |
| Del Coco, R | 1 |
| Loidi, L | 1 |
| Barreiro, F | 1 |
| Calvo, C | 1 |
| Lado-Abeal, J | 1 |
| Araújo-Vilar, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cyclophosphamide in the Treatment of Panniculitis Associated Acquired Lipodystrophy Syndrome With Type 1 Diabetes[NCT03936829] | 10 participants (Anticipated) | Interventional | 2019-04-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for pioglitazone and Berardinelli Syndrome
| Article | Year |
|---|---|
Acquired generalised lipodystrophy and type 1 diabetes mellitus in a child: a rare and implacable association.
Topics: Anticholesteremic Agents; Child; Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; In | 2018 |
An unusual cause of delayed puberty: Berardinelli- Seip syndrome.
Topics: Administration, Cutaneous; Adolescent; Atorvastatin; Combined Modality Therapy; Diet, Fat-Restricted | 2012 |
Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice.
Topics: Adipocytes; Animals; Cells, Cultured; Energy Metabolism; Female; GTP-Binding Protein gamma Subunits; | 2013 |
The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Adipogenesis; Animals; Cell Differentiation; Cel | 2009 |
Reduced adipogenic gene expression in fibroblasts from a patient with type 2 congenital generalized lipodystrophy.
Topics: Adipogenesis; Adolescent; Blotting, Western; Fibroblasts; Gene Expression; Humans; Lipodystrophy, Co | 2010 |