pioglitazone has been researched along with Autism in 3 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the safety and efficacy of pioglitazone added to risperidone in the treatment of irritability in autistic disorder (AD), we conducted this study." | 9.20 | A pilot double-blind placebo-controlled trial of pioglitazone as adjunctive treatment to risperidone: Effects on aberrant behavior in children with autism. ( Akhondzadeh, S; Farokhnia, M; Ghaleiha, A; Mohammadi, MR; Nikoo, M; Rasa, SM, 2015) |
| "To assess the safety and efficacy of pioglitazone added to risperidone in the treatment of irritability in autistic disorder (AD), we conducted this study." | 5.20 | A pilot double-blind placebo-controlled trial of pioglitazone as adjunctive treatment to risperidone: Effects on aberrant behavior in children with autism. ( Akhondzadeh, S; Farokhnia, M; Ghaleiha, A; Mohammadi, MR; Nikoo, M; Rasa, SM, 2015) |
| "No effective treatment yet exists for autism." | 1.48 | Pioglitazone abolishes autistic-like behaviors via the IL-6 pathway. ( Bernardi, MM; Casarin, RC; Felicio, LF; Kirsten, TB, 2018) |
| "The exact causes for autism are largely unknown, but is has been speculated that immune and inflammatory responses, particularly those of Th2 type, may be involved." | 1.34 | Effect of pioglitazone treatment on behavioral symptoms in autistic children. ( Adams, JB; Boris, M; Edelson, SM; Elice, MW; Feinstein, DL; Goldblatt, A; Kaiser, CC, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kirsten, TB | 1 |
| Casarin, RC | 1 |
| Bernardi, MM | 1 |
| Felicio, LF | 1 |
| Ghaleiha, A | 1 |
| Rasa, SM | 1 |
| Nikoo, M | 1 |
| Farokhnia, M | 1 |
| Mohammadi, MR | 1 |
| Akhondzadeh, S | 1 |
| Boris, M | 1 |
| Kaiser, CC | 1 |
| Goldblatt, A | 1 |
| Elice, MW | 1 |
| Edelson, SM | 1 |
| Adams, JB | 1 |
| Feinstein, DL | 1 |
1 trial available for pioglitazone and Autism
| Article | Year |
|---|---|
A pilot double-blind placebo-controlled trial of pioglitazone as adjunctive treatment to risperidone: Effects on aberrant behavior in children with autism.
Topics: Antipsychotic Agents; Autistic Disorder; Child; Child Behavior Disorders; Child, Preschool; Double-B | 2015 |
2 other studies available for pioglitazone and Autism
| Article | Year |
|---|---|
Pioglitazone abolishes autistic-like behaviors via the IL-6 pathway.
Topics: Animals; Anti-Inflammatory Agents; Autistic Disorder; Drug Evaluation, Preclinical; Female; Interleu | 2018 |
Effect of pioglitazone treatment on behavioral symptoms in autistic children.
Topics: Adolescent; Autistic Disorder; Behavioral Symptoms; Child; Child, Preschool; Cohort Studies; Female; | 2007 |