Page last updated: 2024-11-02

pioglitazone and Atrial Remodeling

pioglitazone has been researched along with Atrial Remodeling in 3 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Atrial Remodeling: Long-term changes in the electrophysiological parameters and/or anatomical structures of the HEART ATRIA that result from prolonged changes in atrial rate, often associated with ATRIAL FIBRILLATION or long periods of intense EXERCISE.

Research Excerpts

ExcerptRelevanceReference
" We sought to investigate the potential effects of pioglitazone, a PPAR-γ activator, on atrial remodeling and atrial fibrillation (AF) inducibility in diabetic rabbits."7.85Pioglitazone attenuates atrial remodeling and vulnerability to atrial fibrillation in alloxan-induced diabetic rabbits. ( Cheng, L; Fu, H; Korantzopoulos, P; Li, G; Li, J; Liu, C; Liu, R; Liu, T; Tse, G; Wang, X, 2017)
" We sought to investigate the potential effects of pioglitazone, a PPAR-γ activator, on atrial remodeling and atrial fibrillation (AF) inducibility in diabetic rabbits."3.85Pioglitazone attenuates atrial remodeling and vulnerability to atrial fibrillation in alloxan-induced diabetic rabbits. ( Cheng, L; Fu, H; Korantzopoulos, P; Li, G; Li, J; Liu, C; Liu, R; Liu, T; Tse, G; Wang, X, 2017)
"It has been demonstrated that atrial remodeling contributes toward atrial fibrillation (AF) maintenance and angiotensin II (AngII) is involved in the pathogenesis of atrial remodeling."3.79Beneficial effects of pioglitazone on atrial structural and electrical remodeling in vitro cellular models. ( Gu, J; Guo, M; Liu, F; Liu, X; Song, ZP; Wang, QX; Zhang, DD, 2013)
"It has been demonstrated that atrial electrical remodeling contributes toward atrial fibrillation (AF) maintenance, and that angiotensin II (AngII) is involved in the pathogenesis of atrial electrical remodeling."1.40Pioglitazone improves potassium channel remodeling induced by angiotensin II in atrial myocytes. ( Gu, J; Hu, W; Liu, X, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, C1
Liu, R1
Fu, H1
Li, J1
Wang, X1
Cheng, L1
Korantzopoulos, P1
Tse, G1
Li, G1
Liu, T1
Gu, J2
Liu, X2
Wang, QX1
Guo, M1
Liu, F1
Song, ZP1
Zhang, DD1
Hu, W1

Other Studies

3 other studies available for pioglitazone and Atrial Remodeling

ArticleYear
Pioglitazone attenuates atrial remodeling and vulnerability to atrial fibrillation in alloxan-induced diabetic rabbits.
    Cardiovascular therapeutics, 2017, Volume: 35, Issue:5

    Topics: Action Potentials; Alloxan; Animals; Atrial Fibrillation; Atrial Remodeling; Diabetes Mellitus, Expe

2017
Beneficial effects of pioglitazone on atrial structural and electrical remodeling in vitro cellular models.
    Journal of molecular and cellular cardiology, 2013, Volume: 65

    Topics: Angiotensin II; Animals; Atrial Remodeling; Cardiotonic Agents; Cell Proliferation; Cyclic AMP Respo

2013
Pioglitazone improves potassium channel remodeling induced by angiotensin II in atrial myocytes.
    Medical science monitor basic research, 2014, Oct-08, Volume: 20

    Topics: Angiotensin II; Animals; Atrial Remodeling; Cell Line; Electrophysiological Phenomena; Gene Expressi

2014