pioglitazone has been researched along with Aortic Incompetence in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Excerpt | Relevance | Reference |
---|---|---|
"Treatment with pioglitazone prevented abnormal valve calcification, but did not protect valve function." | 1.42 | Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in Mice. ( Baumbach, GL; Brooks, RM; Chen, B; Chu, Y; Davis, MK; Doshi, H; El Accaoui, RN; Funk, ND; Hajj, GP; Hameed, T; Heistad, DD; Leinwand, LA; Lund, DD; Magida, JA; Song, LS; Weiss, RM; Zimmerman, KA, 2015) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 1 (50.00) | 2.80 |
Authors | Studies |
---|---|
Assmann, AK | 1 |
Goschmer, D | 1 |
Sugimura, Y | 1 |
Chekhoeva, A | 1 |
Barth, M | 1 |
Assmann, A | 1 |
Lichtenberg, A | 1 |
Akhyari, P | 1 |
Hajj, GP | 1 |
Chu, Y | 1 |
Lund, DD | 1 |
Magida, JA | 1 |
Funk, ND | 1 |
Brooks, RM | 1 |
Baumbach, GL | 1 |
Zimmerman, KA | 1 |
Davis, MK | 1 |
El Accaoui, RN | 1 |
Hameed, T | 1 |
Doshi, H | 1 |
Chen, B | 1 |
Leinwand, LA | 1 |
Song, LS | 1 |
Heistad, DD | 1 |
Weiss, RM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of Pioglitazone Treatment in Patient's Calcific Aortic Valve Disease With Mild Aortic Valve Stenosis[NCT05875675] | Phase 2 | 100 participants (Anticipated) | Interventional | 2023-07-01 | Not yet recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 other studies available for pioglitazone and Aortic Incompetence
Article | Year |
---|---|
A Role for Peroxisome Proliferator-Activated Receptor Gamma Agonists in Counteracting the Degeneration of Cardiovascular Grafts.
Topics: Animals; Aortic Valve; Aortic Valve Insufficiency; Bioprosthesis; Calcinosis; Chondrogenesis; Cryopr | 2021 |
Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in Mice.
Topics: Actins; Animals; Aortic Valve; Aortic Valve Insufficiency; Calcinosis; Cell Death; Disease Progressi | 2015 |