pioglitazone has been researched along with Aneurysm, Ruptured in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Aneurysm, Ruptured: The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone treatment reduced the mRNA levels of inflammatory cytokines (monocyte chemoattractant factor-1, interleukin-1, and interleukin-6) that are primarily produced by macrophages in the cerebral arteries." | 1.42 | Protective Role of Peroxisome Proliferator-Activated Receptor-γ in the Development of Intracranial Aneurysm Rupture. ( Furukawa, H; Hashimoto, T; Kitazato, KT; Korai, M; Kuwabara, A; Lawton, MT; Nagahiro, S; Shikata, F; Shimada, K; Tada, Y; Wada, K; Wei, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasan, DM | 1 |
| Starke, RM | 1 |
| Gu, H | 1 |
| Wilson, K | 1 |
| Chu, Y | 1 |
| Chalouhi, N | 1 |
| Heistad, DD | 1 |
| Faraci, FM | 1 |
| Sigmund, CD | 1 |
| Shimada, K | 1 |
| Furukawa, H | 1 |
| Wada, K | 1 |
| Korai, M | 1 |
| Wei, Y | 1 |
| Tada, Y | 1 |
| Kuwabara, A | 1 |
| Shikata, F | 1 |
| Kitazato, KT | 1 |
| Nagahiro, S | 1 |
| Lawton, MT | 1 |
| Hashimoto, T | 1 |
2 other studies available for pioglitazone and Aneurysm, Ruptured
| Article | Year |
|---|---|
Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo.
Topics: Aneurysm, Ruptured; Angiotensin II; Anilides; Animals; Cerebral Arteries; Endothelium, Vascular; Gen | 2015 |
Protective Role of Peroxisome Proliferator-Activated Receptor-γ in the Development of Intracranial Aneurysm Rupture.
Topics: Aneurysm, Ruptured; Anilides; Animals; Cerebral Arteries; Cytokines; Hypoglycemic Agents; Intracrani | 2015 |