pioglitazone has been researched along with Allergy, Drug in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone treatment did not change insulin binding in Wistar fatty rats but increased insulin-stimulated autophosphorylation of insulin receptors to 78% over the level in the control but not the basal state." | 5.28 | Pioglitazone increases insulin sensitivity by activating insulin receptor kinase. ( Egawa, K; Iwanishi, M; Kobayashi, M; Shigeta, Y, 1992) |
| "Catechol-O-methyltransferase (COMT) metabolizes 2-hydroxyestradiol into 2-methoxyestradiol (2-ME); COMT deficiency has shown to be associated with hypertension in men and preeclampsia, the disease associated with hypersensitivity of pressor response against angiotensin II (Ang II)." | 3.85 | Catechol-O-Methyltransferase Deficiency Leads to Hypersensitivity of the Pressor Response Against Angiotensin II. ( Kanasaki, K; Kanasaki, M; Koya, D; Takeda, S; Ueki, N, 2017) |
| "Pioglitazone treatment did not change insulin binding in Wistar fatty rats but increased insulin-stimulated autophosphorylation of insulin receptors to 78% over the level in the control but not the basal state." | 1.28 | Pioglitazone increases insulin sensitivity by activating insulin receptor kinase. ( Egawa, K; Iwanishi, M; Kobayashi, M; Shigeta, Y, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ueki, N | 1 |
| Kanasaki, K | 1 |
| Kanasaki, M | 1 |
| Takeda, S | 1 |
| Koya, D | 1 |
| Kobayashi, M | 1 |
| Iwanishi, M | 1 |
| Egawa, K | 1 |
| Shigeta, Y | 1 |
2 other studies available for pioglitazone and Allergy, Drug
| Article | Year |
|---|---|
Catechol-O-Methyltransferase Deficiency Leads to Hypersensitivity of the Pressor Response Against Angiotensin II.
Topics: Angiotensin II; Animals; Catechol O-Methyltransferase; Drug Hypersensitivity; Female; Hypertension; | 2017 |
Pioglitazone increases insulin sensitivity by activating insulin receptor kinase.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 2; Drug Hypersensitivity; Electrophoresis, Po | 1992 |