Page last updated: 2024-11-02

pioglitazone and Adjuvant Arthritis

pioglitazone has been researched along with Adjuvant Arthritis in 5 studies

Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Research Excerpts

ExcerptRelevanceReference
"The highest doses of rosiglitazone (10 mg/kg/day) or pioglitazone (30 mg/kg/day) were required to reduce fever peaks associated with acute or chronic inflammation, respectively, and to decrease arthritis severity."3.74Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis. ( Bianchi, A; Jouzeau, JY; Koufany, M; Moulin, D; Muresan, M; Netter, P; Sebillaud, S; Weryha, G, 2008)
"Treatment with fenofibrate exerted a better effect on clinical scoring."1.40Fenofibrate vs pioglitazone: Comparative study of the anti-arthritic potencies of PPAR-alpha and PPAR-gamma agonists in rat adjuvant-induced arthritis. ( Jouzeau, JY; Koufany, M; Moulin, D, 2014)
"Adjuvant arthritis was induced by single intra-dermal injection of 0."1.39Anti-arthritic and anti-inflammatory activity of combined pioglitazone and prednisolone on adjuvant-induced arthritis. ( Banerjee, BD; Mediratta, PK; Negi, H; Sharma, KK; Suke, SG, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Li, XF1
Yin, SQ1
Li, H1
Yang, YL1
Chen, X1
Song, B1
Wu, S1
Wu, YY1
Wang, H1
Li, J1
Koufany, M3
Chappard, D1
Netter, P2
Bastien, C1
Weryha, G2
Jouzeau, JY3
Moulin, D3
Suke, SG1
Negi, H1
Mediratta, PK1
Banerjee, BD1
Sharma, KK1
Bianchi, A1
Muresan, M1
Sebillaud, S1

Other Studies

5 other studies available for pioglitazone and Adjuvant Arthritis

ArticleYear
PPAR-γ alleviates the inflammatory response in TNF-α-induced fibroblast-like synoviocytes by binding to p53 in rheumatoid arthritis.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:2

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Fibrob

2023
The peroxisome proliferator-activated receptor γ agonist pioglitazone preserves bone microarchitecture in experimental arthritis by reducing the interleukin-17-dependent osteoclastogenic pathway.
    Arthritis and rheumatism, 2013, Volume: 65, Issue:12

    Topics: Animals; Arthritis, Experimental; Bone and Bones; Bone Density; Interleukin-17; Male; Osteoclasts; O

2013
Anti-arthritic and anti-inflammatory activity of combined pioglitazone and prednisolone on adjuvant-induced arthritis.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Animals; Ankle; Anti-Inflammatory Agents; Arthritis, Experimental; Body Weight; Disease Progression;

2013
Fenofibrate vs pioglitazone: Comparative study of the anti-arthritic potencies of PPAR-alpha and PPAR-gamma agonists in rat adjuvant-induced arthritis.
    Bio-medical materials and engineering, 2014, Volume: 24, Issue:1 Suppl

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Body Weight; Bone and Bones; Bone Densit

2014
Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis.
    Arthritis research & therapy, 2008, Volume: 10, Issue:1

    Topics: Adiponectin; Adipose Tissue; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Biomarkers;

2008