pioglitazone has been researched along with Acute Kidney Injury in 6 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone is a novel class of oral antidiabetic agents currently used to treat type 2 diabetes mellitus." | 5.38 | Protective effects of pioglitazone on renal ischemia-reperfusion injury in mice. ( Hu, H; Huang, X; Shi, Z; Wang, G; Xi, X; Zou, C, 2012) |
| "Pretreatment with cilostazol or pioglitazone provided significant protection against the I/R-induced renal injury as manifested by the attenuated serum levels of creatinine, blood urea nitrogen and cystatin C." | 1.40 | Cilostazol renoprotective effect: modulation of PPAR-γ, NGAL, KIM-1 and IL-18 underlies its novel effect in a model of ischemia-reperfusion. ( Abdallah, DM; El-Abhar, HS; Ragab, D, 2014) |
| "Pioglitazone was administered for six consecutive days in doses of 15 or 30 mg kg(-1) day(-1), per os (p." | 1.40 | The peroxisome proliferator-activated receptor-γ agonist pioglitazone protects against cisplatin-induced renal damage in mice. ( Bortolatto, CF; Jesse, CR; Nogueira, CW; Prigol, M; Roman, SS; Wilhelm, EA, 2014) |
| "Pioglitazone is a novel class of oral antidiabetic agents currently used to treat type 2 diabetes mellitus." | 1.38 | Protective effects of pioglitazone on renal ischemia-reperfusion injury in mice. ( Hu, H; Huang, X; Shi, Z; Wang, G; Xi, X; Zou, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elshazly, S | 1 |
| Soliman, E | 1 |
| Ragab, D | 1 |
| Abdallah, DM | 1 |
| El-Abhar, HS | 1 |
| Abdel-Rahman, EM | 1 |
| Okusa, MD | 1 |
| Zhang, J | 1 |
| Zhang, Y | 1 |
| Xiao, F | 1 |
| Liu, Y | 1 |
| Wang, J | 1 |
| Gao, H | 1 |
| Rong, S | 1 |
| Yao, Y | 1 |
| Li, J | 1 |
| Xu, G | 1 |
| Hu, H | 1 |
| Zou, C | 1 |
| Xi, X | 1 |
| Shi, Z | 1 |
| Wang, G | 1 |
| Huang, X | 1 |
| Jesse, CR | 1 |
| Bortolatto, CF | 1 |
| Wilhelm, EA | 1 |
| Roman, SS | 1 |
| Prigol, M | 1 |
| Nogueira, CW | 1 |
1 review available for pioglitazone and Acute Kidney Injury
| Article | Year |
|---|---|
Effects of aging on renal function and regenerative capacity.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Aging; Animals; Cellular Senescence; Disease Models, A | 2014 |
5 other studies available for pioglitazone and Acute Kidney Injury
| Article | Year |
|---|---|
PPAR gamma agonist, pioglitazone, rescues liver damage induced by renal ischemia/reperfusion injury.
Topics: Acute Kidney Injury; Animals; Caspase 3; Kidney; Liver; Liver Diseases; Male; Pioglitazone; PPAR gam | 2019 |
Cilostazol renoprotective effect: modulation of PPAR-γ, NGAL, KIM-1 and IL-18 underlies its novel effect in a model of ischemia-reperfusion.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Blood Urea Nitrogen; Caspase 1; Cell Adhesion Mo | 2014 |
The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway.
Topics: Acetylation; Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Cis | 2016 |
Protective effects of pioglitazone on renal ischemia-reperfusion injury in mice.
Topics: Acute Kidney Injury; Animals; Apoptosis; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Hy | 2012 |
The peroxisome proliferator-activated receptor-γ agonist pioglitazone protects against cisplatin-induced renal damage in mice.
Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Catalase; Cisplatin; Creatinine; Glutathione; Glutathio | 2014 |